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Assembly of Nanostructures from Double-Crossover Tiles

Stewart, Jaimie Marie and Subramanian, Hari K. K. and Franco, Elisa (2022) Assembly of Nanostructures from Double-Crossover Tiles. In: Cell-Free Gene Expression: Methods and Protocols. Methods in Molecular Biology. No.2433. Humana Press , New York, NY, pp. 293-302. ISBN 978-1-0716-1997-1.

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Artificial self-assembling RNA scaffolds can be produced from many types of RNA motifs that are rationally designed. These scaffolds are of interest as nanoscale organizers, with applications in drug delivery and synthetic cells. Here we describe design strategies, production methods, and imaging of micrometer-sized RNA nanotubes and lattices that assemble from RNA tiles comprising multiple distinct strands.

Item Type:Book Section
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Franco, Elisa0000-0003-1103-2668
Additional Information:© The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2022. First Online 01 January 2022. Elisa Franco acknowledges support from the National Science Foundation through the CAREER award DMR 1938194. Jaimie Marie Stewart is a Merck Awardee of the Life Sciences Research Foundation.
Funding AgencyGrant Number
Life Sciences Research FoundationUNSPECIFIED
Subject Keywords:RNA, RNA assembly, RNA nanotubes, RNA lattices
Series Name:Methods in Molecular Biology
Issue or Number:2433
Record Number:CaltechAUTHORS:20220131-647467800
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:113183
Deposited By: Tony Diaz
Deposited On:01 Feb 2022 18:41
Last Modified:01 Feb 2022 18:41

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