Cable, Jennifer and Rappuoli, Rino and Klemm, Elizabeth J. and Kang, Gagandeep and Mutreja, Ankur and Wright, Gavin J. and Pizza, Mariagrazia and Ajay Castro, Sowmya and Hoffmann, Joseph P. and Alter, Galit and Carfi, Andrea and Pollard, Andrew J. and Krammer, Florian and Gupta, Ravindra K. and Wagner, Caroline E. and Machado, Viviane and Modjarrad, Kayvon and Corey, Lawrence and Gilbert, Peter B. and Dougan, Gordon and Lurie, Nicole and Bjorkman, Pamela J. and Chiu, Christopher and Nemes, Elisa and Gordon, Stephen B. and Steer, Andrew C. and Rudel, Thomas and Blish, Catherine A. and Sandberg, John Tyler and Brennan, Kiva and Klugman, Keith P. and Stuart, Lynda M. and Madhi, Shabir A. and Karp, Christopher L. (2022) Innovative vaccine approaches—a Keystone Symposia report. Annals of the New York Academy of Sciences, 1511 (1). pp. 59-86. ISSN 0077-8923. doi:10.1111/nyas.14739. https://resolver.caltech.edu/CaltechAUTHORS:20220202-543652000
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Abstract
The rapid development of COVID-19 vaccines was the result of decades of research to establish flexible vaccine platforms and understand pathogens with pandemic potential, as well as several novel changes to the vaccine discovery and development processes that partnered industry and governments. And while vaccines offer the potential to drastically improve global health, low-and-middle-income countries around the world often experience reduced access to vaccines and reduced vaccine efficacy. Addressing these issues will require novel vaccine approaches and platforms, deeper insight how vaccines mediate protection, and innovative trial designs and models. On June 28–30, 2021, experts in vaccine research, development, manufacturing, and deployment met virtually for the Keystone eSymposium “Innovative Vaccine Approaches” to discuss advances in vaccine research and development.
| Item Type: | Article | ||||||
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| Additional Information: | © 2022 New York Academy of Sciences. Issue Online: 16 May 2022; Version of Record online: 14 January 2022; Manuscript accepted: 03 December 2021; Manuscript received: 03 December 2021. The authors declare no competing interests. | ||||||
| Group: | COVID-19 | ||||||
| Subject Keywords: | correlates of protection; COVID-19; human challenge studies; influenza; pneumococcal disease; streptococcus; vaccines; vaccine equity | ||||||
| Issue or Number: | 1 | ||||||
| DOI: | 10.1111/nyas.14739 | ||||||
| Record Number: | CaltechAUTHORS:20220202-543652000 | ||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20220202-543652000 | ||||||
| Official Citation: | Cable, J., Rappuoli, R., Klemm, E.J., Kang, G., Mutreja, A., Wright, G.J., Pizza, M., Castro, S.A., Hoffmann, J.P., Alter, G., Carfi, A., Pollard, A.J., Krammer, F., Gupta, R.K., Wagner, C.E., Machado, V., Modjarrad, K., Corey, L., B. Gilbert, P., Dougan, G., Lurie, N., Bjorkman, P.J., Chiu, C., Nemes, E., Gordon, S.B., Steer, A.C., Rudel, T., Blish, C.A., Sandberg, J.T., Brennan, K., Klugman, K.P., Stuart, L.M., Madhi, S.A. and Karp, C.L. (2022), Innovative vaccine approaches—a Keystone Symposia report. Ann. N.Y. Acad. Sci., 1511: 59-86. https://doi.org/10.1111/nyas.14739 | ||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||
| ID Code: | 113226 | ||||||
| Collection: | CaltechAUTHORS | ||||||
| Deposited By: | George Porter | ||||||
| Deposited On: | 03 Feb 2022 00:06 | ||||||
| Last Modified: | 19 May 2022 16:58 |
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