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CAD we share? Publishing reproducible microscope hardware

Diederich, Benedict and Müllenbroich, Caroline and Vladimirov, Nikita and Bowman, Richard and Stirling, Julian and Reynaud, Emmanuel G. and Andreev, Andrey (2022) CAD we share? Publishing reproducible microscope hardware. Nature Methods . ISSN 1548-7091. doi:10.1038/s41592-022-01484-5. (In Press)

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Here we discuss barriers to reproducibility in regard to microscopes and related hardware, along with best practices for sharing novel designs created using computer-aided design (CAD). We hope to start a fruitful community discussion on how instrument development, especially in microscopy, can become more open and reproducible, ultimately leading to better, more trustworthy science.

Item Type:Article
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URLURL TypeDescription ReadCube access
Diederich, Benedict0000-0003-0453-6286
Müllenbroich, Caroline0000-0003-0113-8573
Vladimirov, Nikita0000-0002-1159-0689
Bowman, Richard0000-0002-1531-8199
Stirling, Julian0000-0002-8270-9237
Reynaud, Emmanuel G.0000-0003-1502-661X
Andreev, Andrey0000-0002-7833-1390
Additional Information:© 2022 Nature Publishing Group. Published: 04 May 2022. The authors thank for comments Pete Dahlberg, Davis Perez, Jim Haseloff, Kay Oliver Schink and Scott E. Fraser. M.C.M. acknowledges a Marie Skłodowska-Curie fellowship (MSCA-IF-EF-ST grant agreement no. 842893). N.V. is supported by URPP Adaptive Brain Circuits in Development and Learning (AdaBD). R.W.B. and J.S. acknowledge financial support from the Royal Society (URF\R1\180153, RGF\EA\181034) and EPSRC (EP/R013969/1, EP/R011443/1). Data availability: Data presented in Fig. 2 are available as Source Data and at the GitHub repository ( Source data are provided with this paper. Contributions: All authors contributed equally. The authors declare no competing interests. Peer review information: Nature Methods thanks Alfred Millett-Sikking and the other, anonymous, reviewer(s) for their contribution to the peer review of this work.
Funding AgencyGrant Number
Marie Curie Fellowship842893
University of ZürichUNSPECIFIED
Royal SocietyURF\R1\180153
Royal SocietyRGF\EA\181034
Engineering and Physical Sciences Research Council (EPSRC)EP/R013969/1
Engineering and Physical Sciences Research Council (EPSRC)EP/R011443/1
Subject Keywords:Biological techniques; Scientific community
Record Number:CaltechAUTHORS:20220509-118869200
Persistent URL:
Official Citation:Diederich, B., Müllenbroich, C., Vladimirov, N. et al. CAD we share? Publishing reproducible microscope hardware. Nat Methods (2022).
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:114653
Deposited By: Tony Diaz
Deposited On:09 May 2022 19:31
Last Modified:09 May 2022 19:31

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