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Molecular Contrast Optical Coherence Tomography: A Review

Yang, Changhuei (2005) Molecular Contrast Optical Coherence Tomography: A Review. Photochemistry and Photobiology, 81 (2). pp. 215-237. ISSN 0031-8655.

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This article reviews the current state of research on the use of molecular contrast agents in optical coherence tomography (OCT) imaging techniques. After a brief discussion of the basic principle of OCT and the importance of incorporating molecular contrast agent usage into this imaging modality, we shall present an overview of the different molecular contrast OCT (MCOCT) methods that have been developed thus far. We will then discuss several important practical issues that define the possible range of contrast agent choice, the design criteria for engineered molecular contrast agent and the implementability of a given MCOCT method for clinical or biological applications. We will conclude by outlining a few areas of pursuit that deserve a greater degree of research and development.

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Yang, Changhuei0000-0001-8791-0354
Additional Information:Photochem Photobiol. Author manuscript; available in PMC 2005 November 14. Published in final edited form as: Photochem Photobiol. 2005; 81(2): 215–237. doi: 10.1562/2004-08-06-IR-266 The author gratefully acknowledges useful comments from Brian Applegate (Duke University), Stephen Boppart (University of Illinois at Urbana-Champaign), Zhongping Chen (UC Irvine), Eric Potma (Harvard University), Zahid Yaqoob (Caltech), Xin Heng (Caltech), Fei Wang (Caltech). The author also thanks the various authors of the original MCOCT papers for permission to use their figures in this review.
Issue or Number:2
Record Number:CaltechAUTHORS:YANpp05
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ID Code:1149
Deposited By: Archive Administrator
Deposited On:23 Dec 2005
Last Modified:09 Mar 2020 13:19

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