Petrovic, Stefan and Hoelz, André (2022) Forced entry into the nucleus. Nature Cell Biology, 24 (6). pp. 810-812. ISSN 1465-7392. PMCID PMC9348904. doi:10.1038/s41556-022-00939-3. https://resolver.caltech.edu/CaltechAUTHORS:20220615-392838600
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Abstract
The nuclear pore complex (NPC) regulates transport of macromolecules into and out of the nucleus. A study now shows that mechanical force applied on the nucleus affects the transport rates across the NPC diffusion barrier, modulating the nuclear localization of certain cargos.
Item Type: | Article | ||||||||||||
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Additional Information: | © 2022 Nature Publishing Group. Published 09 June 2022. The authors declare no competing interests. | ||||||||||||
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Subject Keywords: | Mechanotransduction; Nuclear pore complex; Protein translocation | ||||||||||||
Issue or Number: | 6 | ||||||||||||
PubMed Central ID: | PMC9348904 | ||||||||||||
DOI: | 10.1038/s41556-022-00939-3 | ||||||||||||
Record Number: | CaltechAUTHORS:20220615-392838600 | ||||||||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20220615-392838600 | ||||||||||||
Official Citation: | Petrovic, S., Hoelz, A. Forced entry into the nucleus. Nat Cell Biol 24, 810–812 (2022). https://doi.org/10.1038/s41556-022-00939-3 | ||||||||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||||||||
ID Code: | 115167 | ||||||||||||
Collection: | CaltechAUTHORS | ||||||||||||
Deposited By: | Tony Diaz | ||||||||||||
Deposited On: | 17 Jun 2022 19:19 | ||||||||||||
Last Modified: | 16 Aug 2022 22:03 |
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