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Effects of discrete nuclear u.v-microbeam irradiation on herpes virus and SV40 infection

Deák, I. I. and Defendi, V. (1975) Effects of discrete nuclear u.v-microbeam irradiation on herpes virus and SV40 infection. Journal of Cell Science, 17 (3). pp. 531-538. ISSN 0021-9533.

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The requirement for a nucleolus in the expression of structural genes of nuclear viruses was examined by means of experiments in which the nucleolus or other parts of the nucleus was inactivated by a microbean of unltraviolet light. These experiments showed that the expression of such genes is not dependent on cucleolar function. This conclusion is discussed in the light of previous experiments in which similar inactiviation of nucleolus was shown to prevent the expression of cellular structural genes.

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Additional Information:Copyright © 1975 by Company of Biologists. (Received 15 October 1974) This work was done while I.I.D. held a Grocers' Company Research Fellowship at New College, Oxford. We thank Professor Henry Harris for advice and Mrs J.P. McAvoy for technical assistance.
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Imperical Cancer FundUNSPECIFIED
Grocers' Company Research FellowshipUNSPECIFIED
Issue or Number:3
Record Number:CaltechAUTHORS:DEAjcs75
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:11634
Deposited By: Archive Administrator
Deposited On:14 Sep 2008 05:53
Last Modified:03 Oct 2019 00:21

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