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Temperature-sensitive breakdown in vivo of polysomes with mutants of Chlamydomonas reinhardii

Cross, John and McMahon, Daniel (1976) Temperature-sensitive breakdown in vivo of polysomes with mutants of Chlamydomonas reinhardii. Molecular and General Genetics MGG, 147 (2). pp. 169-177. ISSN 0026-8925. doi:10.1007/bf00267568. https://resolver.caltech.edu/CaltechAUTHORS:20221004-680171300.4

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Abstract

Two temperature-sensitive mutants of Chlamydomonas reinhardii Dangeard which are defective in protein synthesis were examined. Both show breakdown of their polysomes at the restrictive temperature into monosomes which do not contain fragments of mRNA. Many of the ribosomes still contain nascent peptides able to react with puromycin. The polysome breakdown involves only cytoplasmic (80S) ribosomes and is prevented or reversed when ribosome translocation is inhibited with cyloheximide.


Item Type:Article
Related URLs:
URLURL TypeDescription
https://doi.org/10.1007/bf00267568DOIArticle
Issue or Number:2
DOI:10.1007/bf00267568
Record Number:CaltechAUTHORS:20221004-680171300.4
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20221004-680171300.4
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:117234
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:12 Oct 2022 23:02
Last Modified:12 Oct 2022 23:02

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