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Molecular Level Sucrose Quantification: A Critical Review

Lara-Cruz, Gustavo A. and Jaramillo-Botero, Andres (2022) Molecular Level Sucrose Quantification: A Critical Review. Sensors, 22 (23). Art. No. 9511. ISSN 1424-8220. doi:10.3390/s22239511.

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Sucrose is a primary metabolite in plants, a source of energy, a source of carbon atoms for growth and development, and a regulator of biochemical processes. Most of the traditional analytical chemistry methods for sucrose quantification in plants require sample treatment (with consequent tissue destruction) and complex facilities, that do not allow real-time sucrose quantification at ultra-low concentrations (nM to pM range) under in vivo conditions, limiting our understanding of sucrose roles in plant physiology across different plant tissues and cellular compartments. Some of the above-mentioned problems may be circumvented with the use of bio-compatible ligands for molecular recognition of sucrose. Nevertheless, problems such as the signal-noise ratio, stability, and selectivity are some of the main challenges limiting the use of molecular recognition methods for the in vivo quantification of sucrose. In this review, we provide a critical analysis of the existing analytical chemistry tools, biosensors, and synthetic ligands, for sucrose quantification and discuss the most promising paths to improve upon its limits of detection. Our goal is to highlight the criteria design need for real-time, in vivo, highly sensitive and selective sucrose sensing capabilities to enable further our understanding of living organisms, the development of new plant breeding strategies for increased crop productivity and sustainability, and ultimately to contribute to the overarching need for food security.

Item Type:Article
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Jaramillo-Botero, Andres0000-0003-2844-0756
Additional Information:This work was partially funded by the “OMICAS program: Optimización Multiescala In-silico de Cultivos Agrícolas Sostenibles (Infraestructura y validación en Arroz y Caña de Azúcar)” Scientific Ecosystem belonging to the Colombia Científica Program, sponsored by The World Bank, The Ministry of Science, Technology and Innovation (MINCIENCIAS), ICETEX, the Colombian Ministry of Education and the Colombian Ministry of Commerce, Industry and Tourism, under GRANT ID: FP44842-217-2018, OMICAS Award ID: 792-61187.
Funding AgencyGrant Number
Ministerio de Ciencia Tecnología e InnovaciónUNSPECIFIED
Instituto Colombiano de Crédito Educativo y Estudios Técnicos en el Exterior (ICETEX)FP44842-217-2018
Ministerio de Educación Nacional (Colombia)792-61187
Issue or Number:23
Record Number:CaltechAUTHORS:20230103-818063100.67
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:118653
Deposited By: Research Services Depository
Deposited On:30 Jan 2023 19:14
Last Modified:30 Jan 2023 19:14

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