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Physical state of newly synthesized RNA

Bonner, James and Huang, Ru-Chih C. and Maheshwari, Nirmala (1961) Physical state of newly synthesized RNA. Proceedings of the National Academy of Sciences of the United States of America, 47 (10). pp. 1548-1554. ISSN 0027-8424.

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We have earlier reported the enzymatic synthesis of RNA from the four riboside triphosphates by a DNA-containing nucleoprotein of pea embryos.(1) Since the nucleoprotein contains the bulk of the tissue DNA and since it resembles in composition and properties the chromatin obtained directly from the nuclei of pea embryos,(2) we refer to the synthetically active material as chromatin. The RNA newly formed by our system is not liberated as free polynucleotide chains but remains associated with the DNA-containing nucleoprotein from which it may be liberated by heat. The present paper is concerned with the nature of this complex.

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Additional Information:© 1961 by the National Academy of Sciences. Communicated August 16, 1961. Report of work supported in part by U.S. Public Health Service Grants Nos. A-3102, RG-3977, RG-5143 and National Science Foundation Grant No. G-7129.
Funding AgencyGrant Number
Public Health ServiceA-3102
Public Health ServiceRG-3977
Public Health ServiceRG-5143
National Science FoundationG-7129
Issue or Number:10
Record Number:CaltechAUTHORS:BONpnas61
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:11903
Deposited By: Tony Diaz
Deposited On:18 Oct 2008 02:52
Last Modified:03 Oct 2019 00:23

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