Stearn, Allen E. (1926) Amphoteric behavior of complex systems. II. Titration of sulfanilic acid-glycine mixtures. Journal of General Physiology, 10 (2). pp. 325-336. ISSN 0022-1295. PMCID PMC2140892. doi:10.1085/jgp.10.2.325. https://resolver.caltech.edu/CaltechAUTHORS:STEjgp26b
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Abstract
It is the purpose of this and the following paper to test portions of the theory in a more quantitative manner, and in this paper the mutual action of two ampholytes, glycine and sulfanilic acid, is studied by means of titration over a wide pH range. The latter substance was chosen to correspond to the strongly acid nucleic acid in living matter. That it is amphoteric, with a measurable basic ionization constant, is shown in the fourth paper of the series. In fact it has an isoelectric point at a distinctly higher pH, 1.25, than that (0.7) of nucleic acid (2). The glycine used was a preparation from the Eastman Kodak Company; and the sulfanilic acid was a Merck C.P. grade, which was reprecipitated from alkaline solution by hydrochloric acid, washed, and dried.
| Item Type: | Article | |||||||||
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| Additional Information: | © 1926 by The Rockefeller University Press. RUP grants the public the non-exclusive right to copy, distribute, or display the Work under a Creative Commons Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/ and http://creativecommons.org/licenses/by-nc-sa/3.0/legalcode. Accepted on July 26, 1926. Contributions from the Gates Chemical Laboratory, California Institute of Technology, No. 116. | |||||||||
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| Issue or Number: | 2 | |||||||||
| PubMed Central ID: | PMC2140892 | |||||||||
| DOI: | 10.1085/jgp.10.2.325 | |||||||||
| Record Number: | CaltechAUTHORS:STEjgp26b | |||||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:STEjgp26b | |||||||||
| Usage Policy: | RUP grants the public the non-exclusive right to copy, distribute, or display the Work under a Creative Commons Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/ and http://creativecommons.org/licenses/by-nc-sa/3.0/legalcode. | |||||||||
| ID Code: | 12370 | |||||||||
| Collection: | CaltechAUTHORS | |||||||||
| Deposited By: | Archive Administrator | |||||||||
| Deposited On: | 14 Nov 2008 05:40 | |||||||||
| Last Modified: | 08 Nov 2021 22:27 |
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