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Biomechanics of traumatic brain injury

El Sayed, Tamer and Mota, Alejandro and Fraternali, Fernando and Ortiz, Michael (2008) Biomechanics of traumatic brain injury. Computer Methods in Applied Mechanics and Engineering, 197 (51-52). pp. 4692-4701. ISSN 0045-7825. doi:10.1016/j.cma.2008.06.006.

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A biomechanical model for traumatic brain injury and soft tissue damage is presented. A variational constitutive model for soft biological tissues is utilized to reproduce axonal damage and cavitation injury through inelastic deformation. The material response is split into elastoplastic and viscoelastic components, including rate effects, shear and porous plasticity, and finite viscoelasticity. Mechanical damage of brain tissue is classified as volumetric (compression/tension) and shear-type. Finite element simulations of brain injuries are presented, examining frontal and oblique head impacts with external objects. Localization, extension, intensity and reversibility/irreversibility of tissue damage are predicted. Future directions of this work, relating mechanical damage and physiological brain dysfunction, and application to relevant medical and engineering problems are discussed.

Item Type:Article
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URLURL TypeDescription
Fraternali, Fernando0000-0002-7549-6405
Ortiz, Michael0000-0001-5877-4824
Additional Information:© 2008 Elsevier. Received 7 February 2008; revised 12 May 2008; accepted 15 June 2008. Available online 25 June 2008. The support of the Regione Campania, Italy, through the program “Modeling Shape, Structure and Mechanical Behavior of the Skull–Encephalon Complex” is greatly acknowledged. The authors also want to sincerely thank Davide Zuppa, graduate student at the Department of Civil Engineering of the University of Salerno, for his relevant and precious collaboration with the present work.
Funding AgencyGrant Number
Regione CampaniaUNSPECIFIED
Subject Keywords:Brain tissue damage; Finite deformation; Plasticity; Finite viscoelasticity; Diffuse axonal injury; Cavitation injury; Traumatic brain injury
Issue or Number:51-52
Record Number:CaltechAUTHORS:ELScmame08
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:12555
Deposited By: Archive Administrator
Deposited On:12 Dec 2008 19:19
Last Modified:08 Nov 2021 22:29

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