A Caltech Library Service

Evolution of the neural crest viewed from a gene regulatory perspective

Sauka-Spengler, Tatjana and Bronner-Fraser, Marianne (2008) Evolution of the neural crest viewed from a gene regulatory perspective. Genesis, 46 (11). pp. 673-682. ISSN 1526-954X. doi:10.1002/dvg.20436.

Full text is not posted in this repository. Consult Related URLs below.

Use this Persistent URL to link to this item:


Neural crest cells are a vertebrate innovation and form a wide variety of embryonic cell types as diverse as peripheral neurons and facial skeleton. They undergo complex migration and differentiation processes from their site of origin in the developing central nervous system to their final destinations in the periphery. In this review, we summarize recent data on the current formulation of a gene regulatory network underlying neural crest formation and its roots at the base of the vertebrate lineage. Analyzing neural crest formation from a gene regulatory viewpoint provides insights into both the developmental mechanisms and evolutionary origins of this vertebrate-specific cell type.

Item Type:Article
Related URLs:
URLURL TypeDescription 10.1002/dvg.20436DOIArticle
Sauka-Spengler, Tatjana0000-0001-9289-0263
Bronner-Fraser, Marianne0000-0003-4274-1862
Additional Information:© 2008 Wiley-Liss, Inc. Received: 14 May 2008; Revised: 18 July 2008; Accepted: 12 August 2008. Published online 10 November 2008.
Subject Keywords:neural crest; gene regulation; network; evolution; development
Issue or Number:11
Record Number:CaltechAUTHORS:SAUgen08
Persistent URL:
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:12868
Deposited By: Archive Administrator
Deposited On:06 Jan 2009 00:24
Last Modified:08 Nov 2021 22:33

Repository Staff Only: item control page