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TSO1 functions in cell division during Arabidopsis flower development

Liu, Zhongchi and Running, Mark P. and Meyerowitz, Elliot M. (1997) TSO1 functions in cell division during Arabidopsis flower development. Development, 124 (3). pp. 665-672. ISSN 0950-1991.

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We describe an Arabidopsis mutant, tso1, which develops callus-like tissues in place of floral organs. The tso1 floral meristem lacks properly organized three cell layers, and the nuclei of these cells are irregular in size and shape. Further analyses reveal partially formed cell walls and increased DNA ploidy in tso1 floral meristem cells, indicating defects in mitosis and cytokinesis. Our finding that TSO1 is required for organ formation in floral tissues but not in other tissues indicates that TSO1 may encode a floral-specific cell division component, or that TSO1 function is redundant in nonfloral tissues.

Item Type:Article
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Meyerowitz, Elliot M.0000-0003-4798-5153
Additional Information:© 1997 Company of Biologists. (Accepted 29 November 1996) We thank Patrick Koen and Jean Edens for their assistance in TEM, Joshua Levin for the tso1-2 allele, William Friedman for advice on microscopic spectrophotometric measurements and the use of his facilities, Glen Turner, Michael Chu and Mintao Fan for contributions to double mutant construction, confocal microscopy and mapping respectively. We also thank Eric Baehrecke and members of the Meyerowitz lab for critical reading of the manuscript. Z.L. was a DOE-energy Biosciences Research Fellow of the Life Science Research Foundation, and was previously a post-doctoral fellow of Damon Runyon-Walter Winchell Cancer Research Fund. M.P.R. was a Howard Hughes predoctoral fellow. This work was supported by NIH grant GM 45697 to E.M.M.
Funding AgencyGrant Number
Department of Energy (DOE)UNSPECIFIED
Damon Runyon-Walter Winchell Cancer Research FoundationUNSPECIFIED
Howard Hughes Medical Institute (HHMI)UNSPECIFIED
Life Sciences Research FoundationUNSPECIFIED
Subject Keywords:tso1, mitosis, cytokinesis, floral meristem
Issue or Number:3
Record Number:CaltechAUTHORS:LIUdev97
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Official Citation:TSO1 functions in cell division during Arabidopsis flower development Z. Liu, M.P. Running, E.M. Meyerowitz Development 1997 124: 665-672
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:13021
Deposited By: Archive Administrator
Deposited On:15 Jan 2009 22:07
Last Modified:03 Oct 2019 00:33

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