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Developmental Patterning by Mechanical Signals in Arabidopsis

Hamant, Olivier and Heisler, Marcus G. and Jönsson, Henrik and Krupinski, Pawel and Uyttewaal, Magalie and Bokov, Plamen and Corson, Francis and Sahlin, Patrick and Boudaoud, Arezki and Meyerowitz, Elliot M. and Couder, Yves and Traas, Jan (2008) Developmental Patterning by Mechanical Signals in Arabidopsis. Science, 322 (5908). pp. 1650-1655. ISSN 0036-8075. https://resolver.caltech.edu/CaltechAUTHORS:HAMsci08

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[img] Video (QuickTime) (Movie S1. Two types of cortical microtubule behaviors in the shoot apex) - Supplemental Material
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[img] Video (QuickTime) (Movie S2. Simulation of a growing primordium on the flank of a meristem) - Supplemental Material
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[img] Video (QuickTime) (Movie S3. Simulation a growing pin-shaped meristem) - Supplemental Material
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[img] Video (QuickTime) (Movie S4. Cortical microtubules reorient following laser-induced cell ablation) - Supplemental Material
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[img] Video (QuickTime) (Movie S5. Cortical microtubules reorient following tangential stretch in the meristem) - Supplemental Material
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[img] Video (QuickTime) (Movie S6. Cortical microtubules reorient following tangential stretch in the meristem) - Supplemental Material
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Abstract

A central question in developmental biology is whether and how mechanical forces serve as cues for cellular behavior and thereby regulate morphogenesis. We found that morphogenesis at the Arabidopsis shoot apex depends on the microtubule cytoskeleton, which in turn is regulated by mechanical stress. A combination of experiments and modeling shows that a feedback loop encompassing tissue morphology, stress patterns, and microtubule-mediated cellular properties is sufficient to account for the coordinated patterns of microtubule arrays observed in epidermal cells, as well as for patterns of apical morphogenesis.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1126/science.1165594DOIArticle
http://www.sciencemag.org/cgi/content/abstract/322/5908/1650PublisherArticle
ORCID:
AuthorORCID
Heisler, Marcus G.0000-0001-5644-8398
Jönsson, Henrik0000-0003-2340-588X
Meyerowitz, Elliot M.0000-0003-4798-5153
Additional Information:© 2008 American Association for the Advancement of Science. Received for publication 8 September 2008. Accepted for publication 14 November 2008. We thank A. Roeder for critical reading of the manuscript, and P. Barbier de Reuille and IFR128 Platim for help with imaging. Supported by the International Human Frontier Science Program Organization, by U.S. Department of Energy grant FG02-88ER13873 (E.M.M.), by the Balzan Foundation (E.M.M.), and by the Swedish Research Council (H.J.).
Funders:
Funding AgencyGrant Number
Human Frontier Science ProgramUNSPECIFIED
Department of Energy (DOE)DE-FG02-88ER13873
International Balzan FoundationUNSPECIFIED
Swedish Research CouncilUNSPECIFIED
Issue or Number:5908
Record Number:CaltechAUTHORS:HAMsci08
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:HAMsci08
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:13038
Collection:CaltechAUTHORS
Deposited By: Archive Administrator
Deposited On:16 Jan 2009 06:36
Last Modified:03 Oct 2019 00:34

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