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X Chromosome Inversions and Meiosis in Drosophila Melanogaster

Beadle, G. W. and Sturtevant, A. H. (1935) X Chromosome Inversions and Meiosis in Drosophila Melanogaster. Proceedings of the National Academy of Sciences of the United States of America, 21 (6). pp. 384-390. ISSN 0027-8424. PMCID PMC1076611. doi:10.1073/pnas.21.6.384.

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It has been shown above that crossovers between X chromosome segments inverted with respect to one another influence the orientation of the meiotic tetrads in such a way as to eliminate the single crossover chromatids, leaving a normal non-crossover one in the reduced egg nucleus. The more complex results expected from multiple exchange are analyzed and shown to give results in agreement with observation. It seems probable that the scheme outlined in this paper will apply for the case of inversions that do not include the locus of the spindle attachment and for other chromosome aberrations in which crossing-over gives rise to chromatids with two spindle attachments, and where the conditions of meiosis are such that (a) the meiotic spindles are oriented so that the reduced nuclei lie approximately on a single straight line, and (b) only one of the terminal nuclei functions in further development. These conditions obtain in megasporogenesis in most seed plants, as well as in oögenesis in most animals.

Item Type:Article
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Additional Information:© 1935 by the National Academy of Sciences. Communicated April 27, 1935.
Issue or Number:6
PubMed Central ID:PMC1076611
Record Number:CaltechAUTHORS:BEApnas35a
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Official Citation:X Chromosome Inversions and Meiosis in Drosophila Melanogaster G. W. Beadle, A. H. Sturtevant Proceedings of the National Academy of Sciences Jun 1935, 21 (6) 384-390; DOI: 10.1073/pnas.21.6.384
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:13084
Deposited By: Archive Administrator
Deposited On:17 Jan 2009 04:30
Last Modified:08 Nov 2021 22:35

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