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Magnetic Resonance Spectroscopy in Neurological Diagnosis

Tran, Thao and Ross, Brian and Lin, Alexander (2009) Magnetic Resonance Spectroscopy in Neurological Diagnosis. Neurologic Clinics, 27 (1). pp. 21-60. ISSN 0733-8619. doi:10.1016/j.ncl.2008.09.007.

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In this article, we review the role of MRS in neurologic diagnosis and patient care. Technical discussion focuses on the few remaining issues, localization, spectral display, and interpretation because interesting questions surrounding this widely diverse methodology have been resolved, and a single coherent diagnostic MRS protocol can be applied worldwide on clinical MRI scanners. We provide the most diagnostically useful MRS findings and discuss what is lacking for MRS to become a valuable addition to diagnostic evaluation of neurologic problems. Finally, we muse about the still-underappreciated role of MRS as a molecular neuroimaging technique and predict steady growth of this application as hyperpolarization MR technology approaches the clinic.

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Additional Information:Copyright © 2008 Elsevier. Available online 3 December 2008.
Subject Keywords:Magnetic resonance spectroscopy; Chemical shift imaging; Encephalopathy; Hypoxia; Cerebral neoplasms; Efficacy; Evidence based medicine; Hyperpolarization
Issue or Number:1
Record Number:CaltechAUTHORS:TRAnc09
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:13129
Deposited By: Archive Administrator
Deposited On:02 Feb 2009 23:24
Last Modified:08 Nov 2021 22:35

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