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Both sodium channel II and IIA alpha subunits are expressed in rat brain

Ahmed, C. M. lqbal and Auld, Vanessa J. and Lester, Henry A. and Dunn, Robert and Davidson, Norman (1990) Both sodium channel II and IIA alpha subunits are expressed in rat brain. Nucleic Acids Research, 18 (19). p. 5907. ISSN 0305-1048. PMCID PMC332354. doi:10.1093/nar/18.19.5907.

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Complementary DNAs encoding four distinct isoforms of the large (α) subunit of the voltage sensitive sodium channel have been isolated from rat brain mRNA (1,2,3). Two of these, II and HA, differ in only 36 nucleotides within the coding region and in only 6 amino acids (1, 3). Because of the possible functional significance of electrophysiological differences between isoforms, it is important to establish definitively that the sequence differences are not due to cloning artifacts and to estimate the relative prevalence levels of the two mRNAs in rat brain.

Item Type:Article
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URLURL TypeDescription CentralArticle
Lester, Henry A.0000-0002-5470-5255
Additional Information:© 1990 Oxford University Press. Submitted August 31, 1990.
Issue or Number:19
PubMed Central ID:PMC332354
Record Number:CaltechAUTHORS:AHMnar90
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:13228
Deposited By: Tony Diaz
Deposited On:06 Feb 2009 05:33
Last Modified:08 Nov 2021 22:36

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