Soltani, Alireza and Wang, Xiao-Jing (2008) From biophysics to cognition: reward-dependent adaptive choice behavior. Current Opinion in Neurobiology, 18 (2). pp. 209-216. ISSN 0959-4388. doi:10.1016/j.conb.2008.07.003. https://resolver.caltech.edu/CaltechAUTHORS:SOLcoin08
![]() |
PDF
- Published Version
Restricted to Repository administrators only See Usage Policy. 450kB |
Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:SOLcoin08
Abstract
In neurobiological studies of various cognitive abilities, neuroscientists use mathematical models to fit behavioral data from well-controlled experiments and look for neural activities that are correlated with parameters in those models. The pinpointed neural correlates are often taken as evidence that a given task is performed according to the prescription of the applied model, and the relevant brain areas encode parameters of such a model. However, to go beyond correlations toward causal understanding, it is necessary to elucidate at multiple levels the neural circuit mechanisms of cognitive processes. This review focuses on recent studies of reward-based decision-making that have begun to tackle this challenge.
Item Type: | Article | ||||||
---|---|---|---|---|---|---|---|
Related URLs: |
| ||||||
Additional Information: | © 2008 Published by Elsevier Ltd. Available online 21 August 2008. This work was supported by NIH grants MH073246. We thank Zahra Ayubi and Daeyeol Lee for comments on the manuscript. | ||||||
Funders: |
| ||||||
Subject Keywords: | anterior cingulate cortex; term synaptic depression; dopamine neurons encode; mixed-strategy game; decision-making; matching behavior; prefrontal cortex; corticostriatal synapses; receptor activation; superior colliculus | ||||||
Issue or Number: | 2 | ||||||
DOI: | 10.1016/j.conb.2008.07.003 | ||||||
Record Number: | CaltechAUTHORS:SOLcoin08 | ||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:SOLcoin08 | ||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||
ID Code: | 13378 | ||||||
Collection: | CaltechAUTHORS | ||||||
Deposited By: | Tony Diaz | ||||||
Deposited On: | 24 Apr 2009 17:21 | ||||||
Last Modified: | 08 Nov 2021 22:37 |
Repository Staff Only: item control page