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The Neuroscience Information Framework: A Data and Knowledge Environment for Neuroscience

Gardner, Daniel and Akil, Huda and Ascoli, Giorgio A. and Bowden, Douglas M. and Bug, William and Donohue, Duncan E. and Goldberg, David H. and Grafstein, Bernice and Grethe, Jeffrey S. and Gupta, Amarnath and Halavi, Maryam and Kennedy, David N. and Marenco, Luis and Martone, Maryann E. and Miller, Perry L. and Müller, Hans-Michael and Robert, Adrian and Shepherd, Gordon M. and Sternberg, Paul W. and Van Essen, David C. and Williams, Robert W. (2008) The Neuroscience Information Framework: A Data and Knowledge Environment for Neuroscience. Neuroinformatics, 6 (3). pp. 149-160. ISSN 1539-2791. PMCID PMC2661130.

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With support from the Institutes and Centers forming the NIH Blueprint for Neuroscience Research, we have designed and implemented a new initiative for integrating access to and use of Web-based neuroscience resources: the Neuroscience Information Framework. The Framework arises from the expressed need of the neuroscience community for neuroinformatic tools and resources to aid scientific inquiry, builds upon prior development of neuroinformatics by the Human Brain Project and others, and directly derives from the Society for Neuroscience’s Neuroscience Database Gateway. Partnered with the Society, its Neuroinformatics Committee, and volunteer consultant-collaborators, our multi-site consortium has developed: (1) a comprehensive, dynamic, inventory of Web-accessible neuroscience resources, (2) an extended and integrated terminology describing resources and contents, and (3) a framework accepting and aiding concept-based queries. Evolving instantiations of the Framework may be viewed at,, and other sites as they come on line.

Item Type:Article
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URLURL TypeDescription ReadCube access CentralArticle
Sternberg, Paul W.0000-0002-7699-0173
Van Essen, David C.0000-0001-7044-4721
Additional Information:© The Author(s) 2008. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. Received: 15 August 2008 Accepted: 26 August 2008 Published online: 23 October 2008. This project has been funded in whole or in part through the NIH Blueprint for Neuroscience Research with Federal funds from the National Institute on Drug Abuse, National Institutes of Health, Department of Health and Human Services, under Contract No. HHSN271200577531C. The Neuroscience Information Framework team gratefully acknowledges the support of volunteer consultant-collaborators and friends, and The Society for Neuroscience. Early development of the SfN Neuroscience Database Gateway was supported by the Society for Neuroscience by means of a generous gift from Paul Allen and Jody Patton and by contract (NIH Order No. 263-MD-409125-1) from NIMH, NINDS, and NIDA. We thank C. Wren for the epitaph adaptable as the Information Sharing Statement. The Advisory Committee consists of Huda Akil, Giorgio Ascoli, Daniel Gardner, Bernice Grafstein, Maryann E. Martone, Gordon Shepherd, Paul Sternberg, David C. Van Essen, and Robert W. Williams.
Funding AgencyGrant Number
National Institute on Drug AbuseUNSPECIFIED
Society for NeuroscienceUNSPECIFIED
Subject Keywords:neurodatabases; data sharing; terminologies; portals
Issue or Number:3
PubMed Central ID:PMC2661130
Record Number:CaltechAUTHORS:20090501-121556840
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Official Citation:Gardner, D., Akil, H., Ascoli, G.A. et al. Neuroinform (2008) 6: 149.
Usage Policy:Springer Open Choice articles are protected by the Springer Open Choice license, which is compatible with the Creative Commons Attribution License.
ID Code:14132
Deposited By: Tony Diaz
Deposited On:13 Aug 2009 19:37
Last Modified:04 Nov 2019 18:40

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