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Dynamic control of auditory activity during sleep: Correlation between song response and EEG

Nick, Teresa A. and Konishi, Masakazu (2001) Dynamic control of auditory activity during sleep: Correlation between song response and EEG. Proceedings of the National Academy of Sciences of the United States of America, 98 (24). pp. 14012-14016. ISSN 0027-8424. PMCID PMC61158. doi:10.1073/pnas.251525298.

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The song nucleus high vocal center (HVC) sends neural signals for song production and receives auditory input. By using electroencephalography (EEG) to objectively identify wake/sleep state, we show that HVC auditory responses change with physiological states. Comparison of EEG and HVC records revealed that HVC response to auditory stimuli is greatest during slow-wave sleep. During slow-wave sleep, HVC neurons responded preferentially to the bird's own song. Strikingly, both spontaneous and forced waking during sleep caused HVC auditory responses to cease within milliseconds of an EEG-measured state change. State-dependent phenomena in downstream nuclei, such as robustus archistriatalis, are likely to be derivatives of those in HVC.

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Additional Information:© 2001 by the National Academy of Sciences. Contributed by Masakazu Konishi, October 3, 2001. We thank A. Leonardo for assistance with data collection and analysis; E. Akutagawa for expert histological assistance; R. Egnor, S. Shanbhag, C. Malek, B. Christianson, B. Arthur, and M. Schmidt for technical assistance; and A. Doupe, M. Schmidt, M. Stopfer, J.L. Pena, and S. Shanbhag for comments on the manuscript. This work was supported by National Institutes of Health Grant MH55984 (to M.K.). The publication costs of this article were defrayed in part by page charge payment. This article must therefore be hereby marked "advertisement" in accordance with 18 U.S.C. §1734 solely to indicate this fact.
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Subject Keywords:SYSTEM
Issue or Number:24
PubMed Central ID:PMC61158
Record Number:CaltechAUTHORS:NICpnas01
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:1505
Deposited By: Tony Diaz
Deposited On:26 Jan 2006
Last Modified:08 Nov 2021 19:10

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