CaltechAUTHORS
  A Caltech Library Service

Cellular mechanisms for resolving phase ambiguity in the owl's inferior colliculus

Peña, José Luis and Konishi, Masakazu (2000) Cellular mechanisms for resolving phase ambiguity in the owl's inferior colliculus. Proceedings of the National Academy of Sciences of the United States of America, 97 (22). pp. 11787-11792. ISSN 0027-8424. https://resolver.caltech.edu/CaltechAUTHORS:PENpnas00

[img]
Preview
PDF
See Usage Policy.

390Kb

Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:PENpnas00

Abstract

Both mammals and birds use the interaural time difference (ITD) for localization of sound in the horizontal plane. They may localize either real or phantom sound sources, when the signal consists of a narrow frequency band. This ambiguity does not occur with broadband signals. A plot of impulse rates or amplitude of excitatory postsynaptic potentials against ITDs (ITD curve) consists of peaks and troughs. In the external nucleus (ICX) of the owl's inferior colliculus, ITD curves show multiple peaks when the signal is narrow-band, such as tones. Of these peaks, one occurs at ITDi, which is independent of frequency, and others at ITDi +/- T, where T is the tonal period. The ITD curve of the same neuron shows a large peak (main peak) at ITDi and no or small peaks (side peaks) at ITD +/- T, when the signal is broadband. ITD curves for postsynaptic potentials indicate that ICX neurons integrate the results of binaural cross-correlation in different frequency bands. However, the difference between the main and side peaks is small. ICX neurons further enhance this difference in the process of converting membrane potentials to impulse rates. Inhibition also appears to augment the difference between the main and side peaks.


Item Type:Article
Additional Information:Copyright © 2000 by the National Academy of Sciences. This paper was presented at the National Academy of Sciences colloquium "Auditory Neuroscience: Development, Transduction, and Integration," held May 19–21, 2000, at the Arnold and Mabel Beckman Center in Irvine, CA. We thank Teresa Nick and Ben Arthur for critically reading the manuscript, Kourosh Saberi for information about human psychoacoustics, Gene Akutagawa for histological assistance, and Chris Malek for computer matters. This work was supported by National Institutes of Health Grant DC00134.
Subject Keywords:INTERAURAL TIME DIFFERENCE; COMPLEX BINAURAL STIMULI; MEDIAL SUPERIOR OLIVE; LOW-FREQUENCY CELLS; AUDITORY SPACE; NOISE STIMULI; BRAIN-STEM; BARN OWL; NUCLEUS; REPRESENTATION
Issue or Number:22
Record Number:CaltechAUTHORS:PENpnas00
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:PENpnas00
Alternative URL:http://www.pnas.org/cgi/content/abstract/97/22/11787
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:1573
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:31 Jan 2006
Last Modified:02 Oct 2019 22:44

Repository Staff Only: item control page