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Angelman Syndrome: Finding the Lost Arc

Tai, Hwan-Ching and Schuman, Erin M. (2010) Angelman Syndrome: Finding the Lost Arc. Cell, 140 (5). pp. 608-610. ISSN 0092-8674.

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Angelman syndrome is a neurodevelopmental disorder caused by mutations in the maternally inherited UBE3A gene, which encodes a ubiquitin ligase. Greer et al. (2010) now identify a UBE3A substrate called Arc that promotes endocytosis of neuronal AMPA receptors, providing insight into synaptic defects that may underlie the cognitive deficits in Angelman syndrome.

Item Type:Article
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URLURL TypeDescription CentralUNSPECIFIED
Schuman, Erin M.0000-0002-7053-1005
Additional Information:© 2010 Elsevier. Available online 4 March 2010.
Issue or Number:5
Record Number:CaltechAUTHORS:20100324-111303412
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Official Citation:Angelman Syndrome: Finding the Lost Arc Tai, Hwan-Ching; Schuman, Erin M. doi:10.1016/j.cell.2010.02.019 (volume 140 issue 5 pp.608 - 610)
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:17789
Deposited By: Jason Perez
Deposited On:30 Mar 2010 23:04
Last Modified:09 Mar 2020 13:19

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