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An auxin-driven polarized transport model for phyllotaxis

Jönsson, Henrik and Heisler, Marcus G. and Shapiro, Bruce E. and Meyerowitz, Elliot M. and Mjolsness, Eric (2006) An auxin-driven polarized transport model for phyllotaxis. Proceedings of the National Academy of Sciences of the United States of America, 103 (5). pp. 1633-1638. ISSN 0027-8424. PMCID PMC1326488. https://resolver.caltech.edu/CaltechAUTHORS:JONpnas06

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Abstract

Recent studies show that plant organ positioning may be mediated by localized concentrations of the plant hormone auxin. Auxin patterning in the shoot apical meristem is in turn brought about by the subcellular polar distribution of the putative auxin efflux mediator, PIN1. However, the question of what signals determine PIN1 polarization and how this gives rise to regular patterns of auxin concentration remains unknown. Here we address these questions by using mathematical modeling combined with confocal imaging. We propose a model that is based on the assumption that auxin influences the polarization of its own efflux within the meristem epidermis. We show that such a model is sufficient to create regular spatial patterns of auxin concentration on systems with static and dynamic cellular connectivities, the latter governed by a mechanical model. We also optimize parameter values for the PIN1 dynamics by using a detailed auxin transport model, for which parameter values are taken from experimental estimates, together with a template consisting of cell and wall compartments as well as PIN1 concentrations quantitatively extracted from confocal data. The model shows how polarized transport can drive the formation of regular patterns.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1326488/PubMed CentralArticle
http://www.pnas.org/content/103/5/1633/suppl/DC1PublisherSupporting Information
https://doi.org/10.1073/pnas.0509839103DOIUNSPECIFIED
https://doi.org/10.1073/pnas.0509839103DOIUNSPECIFIED
ORCID:
AuthorORCID
Jönsson, Henrik0000-0003-2340-588X
Heisler, Marcus G.0000-0001-5644-8398
Meyerowitz, Elliot M.0000-0003-4798-5153
Additional Information:© 2006 National Academy of Sciences. Freely available online through the PNAS open access option. Contributed by Elliot M. Meyerowitz, November 12, 2005. Published online before print January 13, 2006, 10.1073/pnas.0509839103 We thank Christophe Godin, Przemyslaw Prusinkiewicz, and Jan Traas for discussions and Jan Traas for sharing unpublished results. This research was supported by U.S. National Science Foundation FIBR Award EF-0330786 and U.S. Department of Energy Award FG0288ER13873. H.J. was supported in part by the Knut and Alice Wallenberg Foundation through Swegene (Lund, Sweden). Author contributions: H.J., M.G.H., B.E.S., E.M.M., and E.M. designed research; H.J., M.G.H., B.E.S., and E.M. performed research; H.J., M.G.H., B.E.S., E.M.M., and E.M. analyzed data; and H.J. and M.G.H. wrote the paper. Conflict of interest statement: No conflicts declared.
Funders:
Funding AgencyGrant Number
NSFEF-0330786
Department of Energy (DOE)DE-FG02-88ER13873
Knut and Alice Wallenberg FoundationUNSPECIFIED
Subject Keywords:Arabidopsis thaliana; computable plant; dynamical model; pattern formation; meristem
Issue or Number:5
PubMed Central ID:PMC1326488
Record Number:CaltechAUTHORS:JONpnas06
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:JONpnas06
Official Citation:Henrik Jönsson, Marcus G. Heisler, Bruce E. Shapiro, Elliot M. Meyerowitz, and Eric Mjolsness An auxin-driven polarized transport model for phyllotaxis PNAS 2006 103 (5) 1633-1638; published ahead of print January 13, 2006, doi:10.1073/pnas.0509839103
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:1783
Collection:CaltechAUTHORS
Deposited By: Archive Administrator
Deposited On:18 Feb 2006
Last Modified:02 Oct 2019 22:46

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