A Caltech Library Service

Compound-Specific δ^(34)S Analysis of Volatile Organics by Coupled GC/Multicollector-ICPMS

Amrani, Alon and Sessions, Alex L. and Adkins, Jess F. (2009) Compound-Specific δ^(34)S Analysis of Volatile Organics by Coupled GC/Multicollector-ICPMS. Analytical Chemistry, 81 (21). pp. 9027-9034. ISSN 0003-2700.

Full text is not posted in this repository. Consult Related URLs below.

Use this Persistent URL to link to this item:


We have developed a highly sensitive and robust method for the analysis of δ^(34)S in individual organic compounds by coupled gas chromatography (GC) and multicollector inductively coupled plasma mass spectrometry (MC-ICPMS). The system requires minimal alteration of commercial hardware and is amenable to virtually all sample introduction methods. Isobaric interference from O_2^+ is minimized by employing dry plasma conditions and is cleanly resolved at all masses using medium resolution on the Thermo Neptune MC-ICPMS. Correction for mass bias is accomplished using standard−sample bracketing with peaks of SF6 reference gas. The precision of measured δ^(34)S values approaches 0.1‰ for analytes containing >40 pmol S and is better than 0.5‰ for those containing as little as 6 pmol S. This is within a factor of 2 of theoretical shot-noise limits. External accuracy is better than 0.3‰. Integrating only the center of chromatographic peaks, rather than the entire peak, offers significant gain in precision and chromatographic resolution with minimal effect on accuracy but requires further study for verification as a routine method. Coelution of organic compounds that do not contain S can cause degraded analytical precision. Analyses of crude oil samples show wide variability in δ^(34)S and demonstrate the robustness and precision of the method in complex environmental samples.

Item Type:Article
Related URLs:
URLURL TypeDescription DOIArticle
Sessions, Alex L.0000-0001-6120-2763
Adkins, Jess F.0000-0002-3174-5190
Additional Information:© 2009 American Chemical Society. Received for review July 24, 2009. Accepted September 21, 2009. Publication Date (Web): October 6, 2009. We thank Nathan Daleska, Alex Gagnon, Seth John, Magdalena Osburn, and Sean Sylva for assistance with instrumentation and experiments; Tim Lyons, Bill Gillooly, Zeev Aizenshtat, and Ward Said Ahamed for S-isotope analyses of organic standards; Yongchun Tang for crude oil samples; Charles Douthitt, Johannes Schweiters, Claudia Bouman, and Shona McSheehy for advice and support in constructing the instrumentation interface and for useful discussions. This work was supported by The Davidow Endowment for Environmental Science and Engineering at Caltech, the Texaco (Prize) postdoctoral fellowship of Caltech to A.A., and NSF Grant OCE-0852362 to J.F.A.
Funding AgencyGrant Number
Davidow Discovery FundUNSPECIFIED
Caltech Texaco Postdoctoral FellowshipUNSPECIFIED
Issue or Number:21
Record Number:CaltechAUTHORS:20100614-153741613
Persistent URL:
Official Citation:Compound-Specific δ34S Analysis of Volatile Organics by Coupled GC/Multicollector-ICPMS Alon Amrani, Alex L. Sessions, Jess F. Adkins Analytical Chemistry 2009 81 (21), 9027-9034
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:18673
Deposited By: Tony Diaz
Deposited On:15 Jul 2010 21:31
Last Modified:24 Feb 2020 10:30

Repository Staff Only: item control page