Chen, Po-Jui and Rodger, Damien C. and Saati, Saloomeh and Humayun, Mark S. and Tai, Yu-Chong (2008) Implantable parylene-based wireless intraocular pressure sensor. In: MEMS 2008 Tucson : 21st IEEE International Conference on Micro Electro Mechanical Systems. Proceedings: IEEE Micro Electro Mechanical Systems. IEEE , Piscataway, NJ, pp. 58-61. ISBN 978-1-4244-1792-6. https://resolver.caltech.edu/CaltechAUTHORS:20100722-110448277
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Abstract
This paper presents a novel implantable, wireless, passive pressure sensor for ophthalmic applications. Two sensor designs incorporating surface-micromachined variable capacitor and variable capacitor/inductor are implemented to realize the pressure sensitive components. The sensor is monolithically microfabricated using parylene as a biocompatible structural material in a suitable form factor for increased ease of intraocular implantation. Pressure responses of the microsensor are characterized on-chip to demonstrate its high pressure sensitivity (> 7000 ppm/mmHg) with mmHg level resolution. An in vivo animal study verifies the biostability of the sensor implant in the intraocular environment after more than 150 days. This sensor will ultimately be implanted at the pars plana or iris of the eye to fulfill continuous intraocular pressure (IOP) monitoring in glaucoma patients.
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| Additional Information: | © 2008 IEEE. This work was supported in part by the Engineering Research Centers Program of the National Science Foundation (Award Number EEC-0310723) and part by Bausch and Lomb. The authors especially thank Dr. Rajat Agrawal and Dr. Rohit Varma for their valuable comments on surgical procedures, and Mr. Trevor Roper for his fabrication assistance. | |||||||||
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| Series Name: | Proceedings: IEEE Micro Electro Mechanical Systems | |||||||||
| DOI: | 10.1109/MEMSYS.2008.4443592 | |||||||||
| Record Number: | CaltechAUTHORS:20100722-110448277 | |||||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20100722-110448277 | |||||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | |||||||||
| ID Code: | 19163 | |||||||||
| Collection: | CaltechAUTHORS | |||||||||
| Deposited By: | Tony Diaz | |||||||||
| Deposited On: | 30 Jul 2010 17:51 | |||||||||
| Last Modified: | 08 Nov 2021 23:50 |
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