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The Hopfield model and its role in the development of synthetic biology

Loettgers, Andrea (2007) The Hopfield model and its role in the development of synthetic biology. In: 2007 IEEE International Joint Conference on Neural Networks. IEEE International Joint Conference on Neural Networks (IJCNN). IEEE , New York, pp. 1470-1475. ISBN 978-1-4244-1379-9.

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Neural network models make extensive use of concepts coming from physics and engineering. How do scientists justify the use of these concepts in the representation of biological systems? How is evidence for or against the use of these concepts produced in the application and manipulation of the models? It will be shown in this article that neural network models are evaluated differently depending on the scientific context and its modeling practice. In the case of the Hopfield model, the different modeling practices related to theoretical physics and neurobiology played a central role for how the model was received and used in the different scientific communities. In theoretical physics, where the Hopfield model has its roots, mathematical modeling is much more common and established than in neurobiology which is strongly experiment driven. These differences in modeling practice contributed to the development of the new field of synthetic biology which introduced a third type of model which combines mathematical modeling and experimenting on biological systems and by doing so mediates between the different modeling practices.

Item Type:Book Section
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Additional Information:© 2007 IEEE.
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INSPEC Accession Number9797961
Series Name:IEEE International Joint Conference on Neural Networks (IJCNN)
Record Number:CaltechAUTHORS:20101001-101229724
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:20245
Deposited By: Tony Diaz
Deposited On:01 Oct 2010 22:11
Last Modified:08 Nov 2021 23:58

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