CaltechAUTHORS
  A Caltech Library Service

Chain ordering of hybrid lipids can stabilize domains in saturated/hybrid/cholesterol lipid membranes

Yamamoto, T. and Brewster, R. and Safran, S. A. (2010) Chain ordering of hybrid lipids can stabilize domains in saturated/hybrid/cholesterol lipid membranes. Europhysics Letters, 91 (2). p. 28002. ISSN 0295-5075. https://resolver.caltech.edu/CaltechAUTHORS:20101026-121025150

[img]
Preview
PDF - Published Version
See Usage Policy.

229Kb

Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:20101026-121025150

Abstract

We use a liquid-crystal model to predict that hybrid lipids (lipids that have one saturated and one unsaturated tail) can stabilize line interfaces between domains in mixed membranes of saturated lipids, hybrid lipids, and cholesterol (SHC membranes). The model predicts the phase separation of SHC membranes with both parabolic and loop binodals depending on the cholesterol concentration, modeled via an effective pressure. In some cases, the hybrid lipids can reduce the line tension to zero in SHC membranes at temperatures that approach the critical temperature as the pressure is increased. The differences in the hybrid saturated tail conformational order in bulk and at the interface are responsible for the reduction of the line tension.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1209/0295-5075/91/28002DOIUNSPECIFIED
http://iopscience.iop.org/0295-5075/91/2/28002/PublisherUNSPECIFIED
Additional Information:© 2010 EPLA. Received 26 May 2010; accepted in final form 8 July 2010; published online 4 August 2010. The authors thank P. Pincus, L. Addadi, D. Andelman, R. Lipowsky, R. Ziblat, and L. Silva for helpful discussions. This research is made possible in part by the historic generosity of the Harold Perlman Family Foundation. This work was supported by the US-Israel Binational Science Foundation and an ISF converging technology grant.
Funders:
Funding AgencyGrant Number
Harold Perlman Family FoundationUNSPECIFIED
US-Israel Binational Science FoundationUNSPECIFIED
Israel Science Foundation (ISF)UNSPECIFIED
Issue or Number:2
Classification Code:PACS: 82.70.Uv; 64.75.Yz; 87.16.D-
Record Number:CaltechAUTHORS:20101026-121025150
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20101026-121025150
Official Citation:T. Yamamoto et al 2010 EPL 91 28002 doi: 10.1209/0295-5075/91/28002
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:20540
Collection:CaltechAUTHORS
Deposited By: Jason Perez
Deposited On:27 Oct 2010 17:01
Last Modified:03 Oct 2019 02:11

Repository Staff Only: item control page