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Functional Compartmentalization and Viewpoint Generalization Within the Macaque Face-Processing System

Freiwald, Winrich A. and Tsao, Doris Y. (2010) Functional Compartmentalization and Viewpoint Generalization Within the Macaque Face-Processing System. Science, 330 (6005). pp. 845-851. ISSN 0036-8075. PMCID PMC3181095.

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Primates can recognize faces across a range of viewing conditions. Representations of individual identity should thus exist that are invariant to accidental image transformations like view direction. We targeted the recently discovered face-processing network of the macaque monkey that consists of six interconnected face-selective regions and recorded from the two middle patches (ML, middle lateral, and MF, middle fundus) and two anterior patches (AL, anterior lateral, and AM, anterior medial). We found that the anatomical position of a face patch was associated with a unique functional identity: Face patches differed qualitatively in how they represented identity across head orientations. Neurons in ML and MF were view-specific; neurons in AL were tuned to identity mirror-symetrically across views, thus achieving partial view invariance; and neurons in AM, the most anterior face patch, achieved almost full view invariance.

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Additional Information:© 2010 American Association for the Advancement of Science. Received for publication 9 July 2010; accepted for publication 14 September 2010. We are grateful to M. Livingstone, S. Moeller, C. Cadieu, and A. Tsao for discussions; N. Schweers for outstanding technical assistance; S. Chang and the late D. Freeman for stimulus programming; the Humboldt Foundation Sofia Kovalevskaya Award, German Science Foundation grant FR 1437/3-1, the German Ministry of Science (Grant 01GO0506, Bremen Center for Advanced Imaging), and NIH 1R01EY019702 for financial support; and the Otto Loewi Minerva Center for logistic support. D.Y.T. is supported by the Alfred Sloan Foundation, the John Merck Foundation, the Searle Foundation, the Klingenstein Foundation, and NSF CAREER Award BCS-0847798. W.A.F. is supported by a Feodor Lynen Research Fellowship from the Alexander von Humboldt Foundation, an Irma T. Hirschl and Monique Weill-Caulier Trusts Award, a Klingenstein Fellowship Award, a Sinsheimer Scholar Award, and a Pew Scholar Award.
Funding AgencyGrant Number
Humboldt Foundation Sofia Kovalevskaya AwardUNSPECIFIED
Deutsche Forschungsgemeinschaft (DFG)FR 1437/3-1
Bundesministerium für Bildung und Forschung (BMBF)01GO0506
Alfred P. Sloan FoundationUNSPECIFIED
Searle Scholars ProgramUNSPECIFIED
Esther A. and Joseph Klingenstein FundUNSPECIFIED
Alexander von Humboldt FoundationUNSPECIFIED
Irma T. Hirschl and Monique Weill-Caulier TrustsUNSPECIFIED
Alexandrine and Alexander Sinsheimer FundUNSPECIFIED
Pew Charitable TrustUNSPECIFIED
Issue or Number:6005
PubMed Central ID:PMC3181095
Record Number:CaltechAUTHORS:20101122-112104073
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Official Citation:Functional Compartmentalization and Viewpoint Generalization Within the Macaque Face-Processing System Winrich A. Freiwald and Doris Y. Tsao Science 5 November 2010: 330 (6005), 845-851. [DOI:10.1126/science.1194908]
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:20945
Deposited By: Jason Perez
Deposited On:03 Dec 2010 19:11
Last Modified:22 Jan 2020 17:22

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