CaltechAUTHORS
  A Caltech Library Service

Reprogramming Directional Cell Motility by Tuning Micropattern Features and Cellular Signals

Kushiro, Keiichiro and Chang, Stephanie and Asthagiri, Anand R. (2010) Reprogramming Directional Cell Motility by Tuning Micropattern Features and Cellular Signals. Advanced Materials, 22 (40). pp. 4516-4519. ISSN 0935-9648. http://resolver.caltech.edu/CaltechAUTHORS:20101207-140642705

[img] PDF - Published Version
Restricted to Repository administrators only
See Usage Policy.

289Kb
[img] Video (QuickTime) (movie1) - Supplemental Material
Restricted to Repository administrators only
See Usage Policy.

2046Kb
[img] Video (QuickTime) (movie2) - Supplemental Material
Restricted to Repository administrators only
See Usage Policy.

1651Kb
[img] Video (QuickTime) (movie3) - Supplemental Material
Restricted to Repository administrators only
See Usage Policy.

740Kb
[img] Video (QuickTime) (movie4) - Supplemental Material
Restricted to Repository administrators only
See Usage Policy.

2532Kb
[img] Video (QuickTime) (movie5) - Supplemental Material
Restricted to Repository administrators only
See Usage Policy.

2239Kb
[img] Video (QuickTime) (movie6) - Supplemental Material
Restricted to Repository administrators only
See Usage Policy.

1610Kb
[img] Video (QuickTime) (movie7) - Supplemental Material
Restricted to Repository administrators only
See Usage Policy.

1502Kb
[img] PDF (suppl) - Supplemental Material
Restricted to Repository administrators only
See Usage Policy.

653Kb

Use this Persistent URL to link to this item: http://resolver.caltech.edu/CaltechAUTHORS:20101207-140642705

Abstract

Simple geometrical constraints of micropatterned substrates can be used to manipulate the direction and directional persistence of motile cells (scale bar: 20 μm). Modulation of the directional bias is demonstrated by altering pattern parameters and signal pathways.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1002/adma.201001619DOIUNSPECIFIED
http://onlinelibrary.wiley.com/doi/10.1002/adma.201001619/abstract;jsessionid=1D8629EF1A8D1F4E814F5698F1BD26C0.d03t02PublisherUNSPECIFIED
Additional Information:© 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. Received: May 3, 2010; Revised: May 20, 2010; Published online: September 3, 2010. This research was funded by the NSF Center for Science and Engineering of Materials at Caltech. We also gratefully acknowledge the technical support and infrastructure provided by the Kavli Nanoscience Institute.
Group:Kavli Nanoscience Institute
Funders:
Funding AgencyGrant Number
NSF Center for Science and Engineering of Materials at CaltechUNSPECIFIED
Subject Keywords:biomaterials; cell engineering; cellular migration; lamellipodia; micropatterning
Record Number:CaltechAUTHORS:20101207-140642705
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20101207-140642705
Official Citation:Kushiro, K., Chang, S. and Asthagiri, A. R. (2010), Reprogramming Directional Cell Motility by Tuning Micropattern Features and Cellular Signals. Advanced Materials, 22: 4516–4519. doi: 10.1002/adma.201001619
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:21221
Collection:CaltechAUTHORS
Deposited By: Jason Perez
Deposited On:07 Dec 2010 23:03
Last Modified:18 Nov 2013 21:39

Repository Staff Only: item control page