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MAOA-L carriers are better at making optimal financial decisions under risk

Frydman, Cary and Camerer, Colin F. and Bossaerts, Peter and Rangel, Antonio (2011) MAOA-L carriers are better at making optimal financial decisions under risk. Proceedings of the Royal Society of London. Series B, Biological Sciences, 278 (1714). pp. 2053-2059. ISSN 0962-8452. http://resolver.caltech.edu/CaltechAUTHORS:20101220-110227095

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Abstract

Genes can affect behaviour towards risks through at least two distinct neurocomputational mechanisms: they may affect the value assigned to different risky options, or they may affect the way in which the brain adjudicates between options based on their value. We combined methods from neuroeconomics and behavioural genetics to investigate the impact that the genes encoding for monoamine oxidase-A (MAOA), the serotonin transporter (5-HTT) and the dopamine D4 receptor (DRD4) have on these two computations. Consistent with previous literature, we found that carriers of the MAOA-L polymorphism were more likely to take financial risks. Our computational choice model, rooted in established decision theory, showed that MAOA-L carriers exhibited such behaviour because they are able to make better financial decisions under risk, and not because they are more impulsive. In contrast, we found no behavioural or computational differences among the 5-HTT and DRD4 polymorphisms.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1098/rspb.2010.2304DOIUNSPECIFIED
http://rspb.royalsocietypublishing.org/content/early/2010/12/02/rspb.2010.2304PublisherUNSPECIFIED
http://www.ncbi.nlm.nih.gov/pubmed/21147794PubMed CentralUNSPECIFIED
ORCID:
AuthorORCID
Camerer, Colin F.0000-0003-4049-1871
Bossaerts, Peter0000-0003-2308-2603
Additional Information:© 2010 The Royal Society. Received October 22, 2010. Accepted November 12, 2010. Advance online article: Published online before print December 8, 2010. Financial support from Betty and Gordon Moore Foundation (A.R., C.C.) is gratefully acknowledged.
Funders:
Funding AgencyGrant Number
Gordon and Betty Moore FoundationUNSPECIFIED
Subject Keywords:neuroeconomics, behavioural genetics, monoamine oxidase-A, risk-taking, decision-making
Record Number:CaltechAUTHORS:20101220-110227095
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20101220-110227095
Official Citation: * Cary Frydman, * Colin Camerer, * Peter Bossaerts, * and Antonio Rangel MAOA-L carriers are better at making optimal financial decisions under riskProc. R. Soc. B published online before print December 8, 2010, doi:10.1098/rspb.2010.2304
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:21436
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:20 Dec 2010 20:02
Last Modified:03 Mar 2016 22:07

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