A Caltech Library Service

Miniature Neural Interface Microdrive using Parylene-coated Layered Manufacturing

Cham, Jorge G. and Wolf, Michael T. and Andersen, Richard A. and Burdick, Joel W. (2006) Miniature Neural Interface Microdrive using Parylene-coated Layered Manufacturing. In: Proceedings of the first IEEE/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics: BioRob 2006. IEEE , Piscataway, NJ, 721 -726 . ISBN 978-1-4244-0039-3.

PDF - Published Version
See Usage Policy.


Use this Persistent URL to link to this item:


This paper describes a prototype neural interface “microdrive” capable of positioning electrodes with micron precision to record signals from active neurons. The prototype is part of ongoing efforts to develop “smart” neural implant devices that can autonomously optimize neural signals for long-term recordings. Such implants will enable new generations of neural prosthetic systems that will allow patients with lost motor function to control external devices through thoughts alone. The prototype presented was constructed using a layered manufacturing (rapid prototyping) method and made bio-compatible through coating of Parylene. The microdrive offers several advantages over much of the current state of the art in neural recording devices and can be used to support studies in both neural prosthetics and general neurophysiology. A companion paper describes the algorithm used to control the device for autonomous operation.

Item Type:Book Section
Related URLs:
URLURL TypeDescription DOIArticle
Andersen, Richard A.0000-0002-7947-0472
Additional Information:© 2006 IEEE. Issue Date: 20-22 Feb. 2006, Date of Current Version: 05 July 2006. This work is supported by NIH, DARPA, NSF, the Boswell Foundation, and the Christopher Reeve Paralysis Foundation. We thank the members of the Andersen lab at Caltech, and also C. Pang, Y. C. Tai, E. Branchaud, and Z. Nenadic.
Funding AgencyGrant Number
Defense Advanced Research Projects Agency (DARPA)UNSPECIFIED
James G. Boswell FoundationUNSPECIFIED
Christopher Reeve Paralysis FoundationUNSPECIFIED
Subject Keywords:neural prosthetics; neural interfaces
Record Number:CaltechAUTHORS:20110214-111636950
Persistent URL:
Official Citation:Cham, J.G.; Wolf, M.T.; Andersen, R.A.; Burdick, J.W.; , "Miniature Neural Interface Microdrive using Parylenecoated Layered Manufacturing," Biomedical Robotics and Biomechatronics, 2006. BioRob 2006. The First IEEE/RAS-EMBS International Conference on , vol., no., pp.721-726, 20-22 Feb. 2006 doi: 10.1109/BIOROB.2006.1639175 URL:
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:22172
Deposited By: Benjamin Perez
Deposited On:14 Feb 2011 22:23
Last Modified:03 Oct 2019 02:35

Repository Staff Only: item control page