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Estimation of elastic and viscous properties of the left ventricle based on annulus plane harmonic behavior

Kheradvar, Arash and Milano, Michele and Gorman, Robert C. and Gorman, Joseph H., III and Gharib, Morteza (2006) Estimation of elastic and viscous properties of the left ventricle based on annulus plane harmonic behavior. In: 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE , Piscataway, NJ, pp. 616-619. ISBN 1-4244-0032-5 . http://resolver.caltech.edu/CaltechAUTHORS:20110225-110616172

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Abstract

Assessment of left ventricular (LV) function with an emphasis on contractility has been a challenge in cardiac mechanics during the recent decades. The LV function is usually described by the LV pressurevolume (P-V) diagram. The standard P-V diagrams are easy to interpret but difficult to obtain and require invasive instrumentation for measuring the corresponding volume and pressure data. In the present study, we introduce a technique that can estimate the viscoelastic properties of the LV based on harmonic behavior of the ventricular chamber and it can be applied non-invasively as well. The estimation technique is based on modeling the actual long axis displacement of the mitral annulus plane toward the cardiac base as a linear damped oscillator with time-varying coefficients. The time-varying parameters of the model were estimated by a standard Recursive Linear Least Squares (RLLS) technique. LV stiffness at end-systole and end diastole was in the range of 61.86-136.00 dyne/g.cm and 1.25-21.02 dyne/g.cm, respectively. The only input used in this model was the long axis displacement of the annulus plane, which can also be obtained non-invasively using tissue Doppler or MR imaging.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1109/IEMBS.2006.259713 DOIUNSPECIFIED
http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=4461826PublisherUNSPECIFIED
Additional Information:© 2006 IEEE. Manuscript received December 15, 2005. This work was supported in part by NIH grants HL-63954, HL-71137, HL-73021 and HL-76560.
Group:GALCIT
Funders:
Funding AgencyGrant Number
NIHHL-63954
NIHHL-71137
NIHHL-73021
NIHHL-76560
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Other Numbering System NameOther Numbering System ID
INSPEC Accession Number9220485
Record Number:CaltechAUTHORS:20110225-110616172
Persistent URL:http://resolver.caltech.edu/CaltechAUTHORS:20110225-110616172
Official Citation:Kheradvar, A.; Milano, M.; Gorman, R.C.; Gorman, J.H.; Gharib, M.; , "Estimation of elastic and viscous properties of the left ventricle based on annulus plane harmonic behavior," Engineering in Medicine and Biology Society, 2006. EMBS '06. 28th Annual International Conference of the IEEE , vol., no., pp.616-619, Aug. 30 2006-Sept. 3 2006 doi: 10.1109/IEMBS.2006.259713 URL: http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=4461826&isnumber=4461641
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:22521
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:25 Feb 2011 21:37
Last Modified:01 Mar 2017 01:38

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