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A Frequency-Shift based CMOS Magnetic Biosensor with Spatially Uniform Sensor Transducer Gain

Wang, Hua and Sideris, Constantine and Hajimiri, Ali (2010) A Frequency-Shift based CMOS Magnetic Biosensor with Spatially Uniform Sensor Transducer Gain. In: 2010 IEEE Custom Integrated Circuits Conference. IEEE Custom Integrated Circuits Conference . IEEE , New York, NY, pp. 1-4. ISBN 978-1-4244-5760-1.

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This paper presents a scalable and ultrasensitive magnetic biosensing scheme based on on-chip LC resonance frequency-shifting. The sensor transducer gain is demonstrated as being location-dependent on the sensing surface and proportional to the local polarization magnetic field strength |B|^2 generated by the sensing inductor. To improve the gain uniformity, a bowl-shape stacked coil together with floating shimming metal is proposed for the inductor design. As an implementation example, a 16-cell sensor array is designed in a 45nm CMOS process. The spatially uniform sensor gain of the array is verified by testing micron-size magnetic particles randomly placed on the sensing surface. The Correlated-Double-Counting (CDC) noise cancellation scheme is also implemented in the presented design, which achieves a noise suppression of 10.6dB with no power overhead. Overall, the presented sensor demonstrates a dynamic range of at least 85.4dB.

Item Type:Book Section
Related URLs:
Sideris, Constantine0000-0002-3042-4889
Hajimiri, Ali0000-0001-6736-8019
Additional Information:© 2010 IEEE. Issue Date: 19-22 September 2010, Date of Current Version: 01 November 2010.
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INSPEC Accession Number11627759
Series Name:IEEE Custom Integrated Circuits Conference
Record Number:CaltechAUTHORS:20110310-094654711
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Official Citation:Hua Wang; Sideris, C.; Hajimiri, A.; , "A frequency-shift based CMOS magnetic biosensor with spatially uniform sensor transducer gain," Custom Integrated Circuits Conference (CICC), 2010 IEEE , vol., no., pp.1-4, 19-22 Sept. 2010 doi: 10.1109/CICC.2010.5617603 URL:
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:22794
Deposited By: Benjamin Perez
Deposited On:10 Mar 2011 17:59
Last Modified:09 Mar 2020 13:19

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