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piRNAs Meet Mitochondria

Aravin, Alexei A. and Chan, David C. (2011) piRNAs Meet Mitochondria. Developmental Cell, 20 (3). pp. 287-288. ISSN 1534-5807.

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zuc/MitoPLD encodes a conserved enzyme that localizes to mitochondria and hydrolyzes the mitochondria-specific lipid cardiolipin. Surprisingly, zuc/MitoPLD activity is required for Piwi-interacting RNA (piRNA)-mediated silencing of transposable elements in fly and mouse germlines, suggesting that signaling from mitochondria influences the piRNA pathway.

Item Type:Article
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URLURL TypeDescription DOIArticle
Chan, David C.0000-0002-0191-2154
Additional Information:© 2011 Elsevier Inc. Available online 14 March 2011.
Issue or Number:3
Record Number:CaltechAUTHORS:20110418-113351861
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Official Citation:Alexei A. Aravin, David C. Chan, piRNAs Meet Mitochondria, Developmental Cell, Volume 20, Issue 3, 15 March 2011, Pages 287-288, ISSN 1534-5807, DOI: 10.1016/j.devcel.2011.03.003.
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:23363
Deposited By: Ruth Sustaita
Deposited On:20 Apr 2011 15:53
Last Modified:24 Feb 2020 10:30

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