CaltechAUTHORS
  A Caltech Library Service

Biological complexity and robustness

Doyle, John C. (2006) Biological complexity and robustness. In: 2006 Bio-, Micro- and Nanosystems Conference. IEEE , Piscataway, NJ, p. 1. ISBN 978-1-4244-0056-0. https://resolver.caltech.edu/CaltechAUTHORS:20110615-105907604

[img]
Preview
PDF - Published Version
See Usage Policy.

111Kb

Use this Persistent URL to link to this item: https://resolver.caltech.edu/CaltechAUTHORS:20110615-105907604

Abstract

This talk will describe qualitatively in as much detail as time allows these features of biological systems and their parallels in technology, using hopefully familiar and concrete examples. The aim is to be accessible to biologists, and not to depend critically on the mathematical framework. A crucial insight is that both evolution and natural selection or engineering design must produce high robustness to uncertain environments and components in order for systems to persist. Yet this allows and even facilitates severe fragility to novel perturbations, particularly those that exploit the very mechanisms providing robustness, and this "robust yet fragile" (RYF) feature must be exploited explicitly in any theory that hopes to scale to large systems. Time permitting, the mathematical research implications will be sketched of this view of "organized complexity" in biology, technology, and mathematics. This view contrasts sharply with that of "emergent complexity" popular in other areas of science in a way that can now be made mathematically precise.


Item Type:Book Section
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1109/BMN.2006.330919 DOIArticle
http://ieeexplore.ieee.org/xpls/abs_all.jsp?arnumber=4129382PublisherArticle
ORCID:
AuthorORCID
Doyle, John C.0000-0002-1828-2486
Additional Information:© 2006 IEEE. Issue Date: 15-18 Jan. 2006. Date of Current Version: 26 March 2007.
Record Number:CaltechAUTHORS:20110615-105907604
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20110615-105907604
Official Citation:Doyle, J.; Brawn, J.G.; , "Biological complexity and robustness," Bio Micro and Nanosystems Conference, 2006. BMN '06 , vol., no., pp.1, 15-18 Jan. 2006 doi: 10.1109/BMN.2006.330919 URL: http://ieeexplore.ieee.org/stamp/stamp.jsp?tp=&arnumber=4129382&isnumber=4126236
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:24013
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:17 Jun 2011 17:34
Last Modified:26 Nov 2019 11:15

Repository Staff Only: item control page