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Algorithmic Self-Assembly of DNA

Winfree, Erik (2006) Algorithmic Self-Assembly of DNA. In: Proceedings of the 2006 International Conference on Microtechnologies in Medicine and Biology. IEEE , Piscataway, NJ, p. 4. ISBN 978-1-4244-0337-0.

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Nucleic acids have proven to be remarkably versatile as an engineering material for chemical tasks including the storage of information, catalyzing reactions creating and breaking bonds, mechanical manipulation using molecular motors, and constructing supramolecular structures. This talk will focus particularly on molecular self-assembly, giving examples of engineered DNA "tiles" that crystallize into two-dimensional sheets, one-dimensional tubes and ribbons, and information-guided patterns such as a Sierpinski triangle and a binary counter. A theme is how cooperative binding can be used to control nucleation and direct selective tile attachment. Such "algorithmic" self-assembly may provide a bottom-up fabrication method for creating complex, well-defined supramolecular structures that can be used as scaffolds or templates for applications such as arranging molecular electronic components into active circuits.

Item Type:Book Section
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Winfree, Erik0000-0002-5899-7523
Additional Information:© 2006 IEEE. Issue Date: 9-12 May 2006; Date of Current Version: 30 July 2007.
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INSPEC Accession Number9296580
Record Number:CaltechAUTHORS:20110810-095116353
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Official Citation:Winfree, E.; , "Algorithmic Self-Assembly of DNA," Microtechnologies in Medicine and Biology, 2006 International Conference on , vol., no., pp.4, 9-12 May 2006
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:24776
Deposited By: Jason Perez
Deposited On:10 Aug 2011 17:15
Last Modified:03 Oct 2019 02:59

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