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Designing proteins for therapeutic applications

Lazar, Greg A. and Marshall, Shannon A. and Plecs, Joseph J. and Mayo, Stephen L. and Desjarlais, John R. (2003) Designing proteins for therapeutic applications. Current Opinion in Structural Biology, 13 (4). pp. 513-518. ISSN 0959-440X. doi:10.1016/S0959-440X(03)00104-0.

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Protein design is becoming an increasingly useful tool for optimizing protein drugs and creating novel biotherapeutics. Recent progress includes the engineering of monoclonal antibodies, cytokines, enzymes and viral fusion inhibitors.

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Mayo, Stephen L.0000-0002-9785-5018
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Additional Information:© 2003 Elsevier Ltd. Available online 19 July 2003. This review comes from a themed issue on Engineering and design. Edited by Sophie E Jackson and Lynne Regan.
Subject Keywords:Animals; Antibodies: Monoclonal; Protein Engineering; Antiviral Agents; Proteins; Humans; Cytokines
Issue or Number:4
Record Number:CaltechAUTHORS:20110913-173425194
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Official Citation:Greg A Lazar, Shannon A Marshall, Joseph J Plecs, Stephen L Mayo, John R Desjarlais, Designing proteins for therapeutic applications, Current Opinion in Structural Biology, Volume 13, Issue 4, August 2003, Pages 513-518, ISSN 0959-440X, 10.1016/S0959-440X(03)00104-0.
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:25330
Deposited By: Marie Ary
Deposited On:23 Sep 2011 23:07
Last Modified:09 Nov 2021 16:32

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