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Regulatory modules that generate biphasic signal response in biological systems

Levchenko, A. and Bruck, J. and Sternberg, P. W. (2004) Regulatory modules that generate biphasic signal response in biological systems. Systems Biology, 1 (1). pp. 139-148. ISSN 1741-2471. doi:10.1049/sb:20045014.

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Biochemical networks might be composed of modules. It is still not clear how biochemical modules can be defined and characterised. Here we propose a functional approach to module definition, considering different classes of biphasic regulation modules, which effect optimal cell response to intermediate signal strength. Each regulation class might possess unique properties that make it especially suitable for particular biological functions.

Item Type:Article
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URLURL TypeDescription
Bruck, J.0000-0001-8474-0812
Sternberg, P. W.0000-0002-7699-0173
Additional Information:© 2004 IEE. Paper first received 5th April and in revised form 15th May 2004.
Issue or Number:1
Record Number:CaltechAUTHORS:20111014-095736081
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Official Citation:Levchenko, A.; Bruck, J.; Sternberg, P.W.; , "Regulatory modules that generate biphasic signal response in biological systems," Systems Biology, IEE Proceedings , vol.1, no.1, pp.139-148, June 2004 doi: 10.1049/sb:20045014 URL:
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:27227
Deposited By: Ruth Sustaita
Deposited On:14 Oct 2011 17:13
Last Modified:09 Nov 2021 16:46

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