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Fracture mechanics model of stone comminution in ESWL and implications for tissue damage

Lokhandwalla, Murtuza and Sturtevant, Bradford (2000) Fracture mechanics model of stone comminution in ESWL and implications for tissue damage. Physics of Medicine and Biology, 45 (7). pp. 1923-1940. ISSN 0031-9155. doi:10.1088/0031-9155/45/7/316.

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Focused shock waves administered during extracorporeal shock-wave lithotripsy (ESWL) cause stone fragmentation. The process of stone fragmentation is described in terms of a dynamic fracture process. As is characteristic of all brittle materials, fragmentation requires nucleation, growth and coalescence of flaws, caused by a tensile or shear stress. The mechanisms, operative in the stone, inducing these stresses have been identified as spall and compression-induced tensile microcracks, nucleating at pre-existing flaws. These mechanisms are driven by the lithotripter-generated shock wave and possibly also by cavitation effects in the surrounding fluid. In this paper, the spall mechanism has been analysed, using a cohesive-zone model for the material. The influence of shock wave parameters, and physical properties of stone, on stone comminution is described. The analysis suggests a potential means to exploit the difference between the stone and tissue physical properties, so as to make stone comminution more effective, without increasing tissue damage.

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Additional Information:© Institute of Physics 2000. Received 20 January 2000; Print publication: Issue 7 (July 2000) We thank Professor G Ravichandran and Professor M Ortiz for their valuable comments on the ideas discussed in this work. This work was supported by NIH grant P01 DK43881.
Issue or Number:7
Record Number:CaltechAUTHORS:LOKpmb00
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:2749
Deposited By: Archive Administrator
Deposited On:25 Apr 2006
Last Modified:08 Nov 2021 19:50

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