Lokhandwalla, Murtuza and Sturtevant, Bradford (2000) Fracture mechanics model of stone comminution in ESWL and implications for tissue damage. Physics of Medicine and Biology, 45 (7). pp. 1923-1940. ISSN 0031-9155. doi:10.1088/0031-9155/45/7/316. https://resolver.caltech.edu/CaltechAUTHORS:LOKpmb00
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Abstract
Focused shock waves administered during extracorporeal shock-wave lithotripsy (ESWL) cause stone fragmentation. The process of stone fragmentation is described in terms of a dynamic fracture process. As is characteristic of all brittle materials, fragmentation requires nucleation, growth and coalescence of flaws, caused by a tensile or shear stress. The mechanisms, operative in the stone, inducing these stresses have been identified as spall and compression-induced tensile microcracks, nucleating at pre-existing flaws. These mechanisms are driven by the lithotripter-generated shock wave and possibly also by cavitation effects in the surrounding fluid. In this paper, the spall mechanism has been analysed, using a cohesive-zone model for the material. The influence of shock wave parameters, and physical properties of stone, on stone comminution is described. The analysis suggests a potential means to exploit the difference between the stone and tissue physical properties, so as to make stone comminution more effective, without increasing tissue damage.
Item Type: | Article | ||||||
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Additional Information: | © Institute of Physics 2000. Received 20 January 2000; Print publication: Issue 7 (July 2000) We thank Professor G Ravichandran and Professor M Ortiz for their valuable comments on the ideas discussed in this work. This work was supported by NIH grant P01 DK43881. | ||||||
Issue or Number: | 7 | ||||||
DOI: | 10.1088/0031-9155/45/7/316 | ||||||
Record Number: | CaltechAUTHORS:LOKpmb00 | ||||||
Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:LOKpmb00 | ||||||
Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | ||||||
ID Code: | 2749 | ||||||
Collection: | CaltechAUTHORS | ||||||
Deposited By: | Archive Administrator | ||||||
Deposited On: | 25 Apr 2006 | ||||||
Last Modified: | 08 Nov 2021 19:50 |
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