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Toward empirical evaluation of left ventricle function: A novel mathematical mapping

Dabiri, J. O. and Gharib, M. (2002) Toward empirical evaluation of left ventricle function: A novel mathematical mapping. In: Second Joint EMBS-BMES Conference 2002. Proceedings of Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE , Piscataway, NJ, pp. 1270-1271. ISBN 0-7803-7612-9.

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A strategy is developed to facilitate quantitative analysis of left ventricle morphology based on clinically measured surface geometry and muscle fiber patterns rather than lower order geometric approximations previously required. A transfer function is derived which maps measured three-dimensional ventricle surfaces and associated muscle fiber patterns to a right circular cylinder, while preserving characteristic kinematics of the system. Functional analysis of ventricular morphology at various stages of the cardiac cycle proceeds by using classical methods on the cylindrical ventricle model, with substantially reduced analytical complexity when compared to similar calculations on the real ventricle shape. Functional morphology of the real ventricle shape at any stage of the cardiac cycle is subsequently deduced by applying the inverse of the transfer function in order to map the computed right circular cylinder back to its corresponding real ventricle shape. Limitations of the method are discussed in the context of real left ventricle performance, and extension of the method for analysis of functional morphology in other biomechanical systems is explored.

Item Type:Book Section
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URLURL TypeDescription DOIArticle
Dabiri, J. O.0000-0002-6722-9008
Gharib, M.0000-0002-2204-9302
Additional Information:© 2002 IEEE. Date of Current Version: 06 January 2003.
Subject Keywords:ventricle, myocardium, mechanics, modeling
Record Number:CaltechAUTHORS:20111102-112552555
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Official Citation:Dabiri, J.O.; Gharib, M.; , "Toward empirical evaluation of left ventricle function: a novel mathematical mapping," Engineering in Medicine and Biology, 2002. 24th Annual Conference and the Annual Fall Meeting of the Biomedical Engineering Society EMBS/BMES Conference, 2002. Proceedings of the Second Joint , vol.2, no., pp. 1270- 1271 vol.2, 2002 doi: 10.1109/IEMBS.2002.1106382 URL:
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:27586
Deposited By: Ruth Sustaita
Deposited On:02 Nov 2011 18:51
Last Modified:25 Apr 2019 14:49

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