Evidence for Interstitial Carbon in Nitrogenase FeMo Cofactor

Spatzal, Thomas and Aksoyoglu, Müge and Zhang, Limei and Andrade, Susana L. A. and Schleicher, Erik and Weber, Stefan and Rees, Douglas C. and Einsle, Oliver (2011) Evidence for Interstitial Carbon in Nitrogenase FeMo Cofactor. Science, 334 (6058). p. 940. ISSN 0036-8075. PMCID PMC3268367. https://resolver.caltech.edu/CaltechAUTHORS:20111207-101914652

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Abstract

The identity of the interstitial light atom in the center of the FeMo cofactor of nitrogenase has been enigmatic since its discovery. Atomic-resolution x-ray diffraction data and an electron spin echo envelope modulation (ESEEM) analysis now provide direct evidence that the ligand is a carbon species.

Item Type:

Article

Related URLs:

URL	URL Type	Description
http://dx.doi.org/10.1126/science.1214025	DOI	Article
http://www.sciencemag.org/content/334/6058/940.abstract	Publisher	Article
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268367/	PubMed Central	Article

ORCID:

Author	ORCID
Spatzal, Thomas	0000-0002-9136-5915
Rees, Douglas C.	0000-0003-4073-1185

Additional Information:

© 2011 American Association for the Advancement of Science. Received 15 September 2011; accepted 19 October 2011. We thank the staff at Swiss Light Source, Villigen, Switzerland, and S. M. Consiglio for assistance with the calculations. The work was supported by Deutsche Forschungsgemeinschaft (grants Ei-520/7 to O.E., An-676/1 to S.L.A.A., and IRTG 1478), Natural Sciences and Engineering Research Council of Canada postdoctoral fellowship to L.Z., NIH (grant GM45162 to D.C.R.), and HHMI (to D.C.R.). The structural model and structure factors have been deposited with the Protein Data Bank (accession code 3U7Q).

Funders:

Funding Agency	Grant Number
Deutsche Forschungsgemeinschaft (DFG)	Ei-520/7
Deutsche Forschungsgemeinschaft (DFG)	An-676/1
Deutsche Forschungsgemeinschaft (DFG)	IRTG 1478
Natural Sciences and Engineering Research Council of Canada (NSERC)	UNSPECIFIED
NIH	GM45162
Howard Hughes Medical Institute (HHMI)	UNSPECIFIED

Other Numbering System:

Other Numbering System Name	Other Numbering System ID
Protein Bank accession code	3U7Q

Issue or Number:

6058

PubMed Central ID:

PMC3268367

Record Number:

CaltechAUTHORS:20111207-101914652

Persistent URL:

https://resolver.caltech.edu/CaltechAUTHORS:20111207-101914652

Official Citation:

Evidence for Interstitial Carbon in Nitrogenase FeMo Cofactor Thomas Spatzal, Müge Aksoyoglu, Limei Zhang, Susana L. A. Andrade, Erik Schleicher, Stefan Weber, Douglas C. Rees, and Oliver Einsle Science 18 November 2011: 940.

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ID Code:

28340

Collection:

CaltechAUTHORS

Deposited By:

Ruth Sustaita

Deposited On:

07 Dec 2011 18:45

Last Modified:

14 Oct 2019 18:22

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