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Human Dorsal Striatum Encodes Prediction Errors during Observational Learning of Instrumental Actions

Cooper, Jeffrey C. and Dunne, Simon and Furey, Teresa and O'Doherty, John P. (2012) Human Dorsal Striatum Encodes Prediction Errors during Observational Learning of Instrumental Actions. Journal of Cognitive Neuroscience, 24 (1). pp. 106-118. ISSN 0898-929X. PMCID PMC3576883. doi:10.1162/jocn_a_00114.

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The dorsal striatum plays a key role in the learning and expression of instrumental reward associations that are acquired through direct experience. However, not all learning about instrumental actions require direct experience. Instead, humans and other animals are also capable of acquiring instrumental actions by observing the experiences of others. In this study, we investigated the extent to which human dorsal striatum is involved in observational as well as experiential instrumental reward learning. Human participants were scanned with fMRI while they observed a confederate over a live video performing an instrumental conditioning task to obtain liquid juice rewards. Participants also performed a similar instrumental task for their own rewards. Using a computational model-based analysis, we found reward prediction errors in the dorsal striatum not only during the experiential learning condition but also during observational learning. These results suggest a key role for the dorsal striatum in learning instrumental associations, even when those associations are acquired purely by observing others.

Item Type:Article
Related URLs:
URLURL TypeDescription CentralArticle
Dunne, Simon0000-0003-4875-7953
O'Doherty, John P.0000-0003-0016-3531
Additional Information:© 2011 Massachusetts Institute of Technology. Posted Online November 21, 2011. The authors gratefully acknowledge financial support from the Wellcome Trust (grant WT087388AIA to J. O. D.) and the Irish Research Council for Science, Engineering, and Technology (to J. C. C.). We thank Sojo Joseph for technical support and the members of the OʼDoherty laboratory for helpful comments.
Funding AgencyGrant Number
Wellcome TrustWT087388AIA
Irish Research Council for Science, Engineering and TechnologyUNSPECIFIED
Issue or Number:1
PubMed Central ID:PMC3576883
Record Number:CaltechAUTHORS:20120106-132044696
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Official Citation:Human Dorsal Striatum Encodes Prediction Errors during Observational Learning of Instrumental Actions Jeffrey C. Cooper, Simon Dunne, Teresa Furey, and John P. O'Doherty Journal of Cognitive Neuroscience 2012 24:1, 106-118
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:28703
Deposited By: Ruth Sustaita
Deposited On:06 Jan 2012 21:54
Last Modified:09 Nov 2021 16:59

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