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Different Representations of Potential and Selected Motor Plans by Distinct Parietal Areas

Cui, He and Andersen, Richard A. (2011) Different Representations of Potential and Selected Motor Plans by Distinct Parietal Areas. Journal of Neuroscience, 31 (49). pp. 18130-18136. ISSN 0270-6474. PMCID PMC3327481. doi:10.1523/JNEUROSCI.6247-10.2011.

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Traditional theories have considered decision making as a separate neural process occurring before action planning. However, recent neurophysiological studies of spatial target selection have suggested that decision making and motor planning may be performed in an integrated manner. It was proposed that multiple potential plans are concurrently formed and the ultimately selected action simultaneously emerges within the same circuits (Shadlen and Newsome, 2001; Cisek and Kalaska, 2010). In the present study, we recorded from the parietal reach region (PRR) and dorsal area 5 (area 5d) in the posterior parietal cortex (PPC) while monkeys performed a nonspatial effector (saccade vs reach) choice task. The results show that PRR encodes potential and selected reach plans whereas area 5d encodes only selected reach plans, suggesting a serial visuomotor cortical circuitry for nonspatial effector decisions. Thus, there appears to be a different flow of processing for decisions and planning for spatial target selection, which is more integrated, and nonspatial effector decisions between eye and limb movements, which are more serial.

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URLURL TypeDescription DOIArticle CentralArticle
Andersen, Richard A.0000-0002-7947-0472
Additional Information:© 2011 the authors. Received Nov. 30, 2010; revised Oct. 5, 2011; accepted Oct. 31, 2011. This work was supported by the National Eye Institute and the James G. Boswell Foundation to R.A.A., and the Alfred P. Sloan Research Fellowship and the Whitehall Foundation to H.C. We thank D. Baldauf, E. Hwang, and G. Mulliken for helpful discussion during the course of this study; I. Kagan for help with MRI; K. Pejsa, and N. Sammons for help with animal handling and training; J. Baer and C. Lindsell for veterinary assistance; V. Shcherbatyuk for computer support; and T. Yao for administrative support. Author contributions: H.C. and R.A.A. designed research; H.C. performed research; H.C. analyzed data; H.C. and R.A.A. wrote the paper.
Funding AgencyGrant Number
National Eye InstituteUNSPECIFIED
James G. Boswell FoundationUNSPECIFIED
Alfred P. Sloan Research FellowshipUNSPECIFIED
Whitehall FoundationUNSPECIFIED
Issue or Number:49
PubMed Central ID:PMC3327481
Record Number:CaltechAUTHORS:20120210-133552159
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Official Citation:Different Representations of Potential and Selected Motor Plans by Distinct Parietal Areas He Cui, Richard A. Andersen Journal of Neuroscience 7 December 2011, 31 (49) 18130-18136; DOI: 10.1523/JNEUROSCI.6247-10.2011
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:29241
Deposited By: Tony Diaz
Deposited On:21 Mar 2012 20:35
Last Modified:09 Nov 2021 17:05

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