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CLAVATA1, a regulator of meristem and flower development in Arabidopsis

Clark, Steven E. and Running, Mark P. and Meyerowitz, Elliot M. (1993) CLAVATA1, a regulator of meristem and flower development in Arabidopsis. Development, 119 (2). pp. 397-418. ISSN 0950-1991.

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We have investigated the effects on plant development of mutations in the Arabidopsis thaliana CLAVATA1 gene. In clavata1 plants, vegetative, inflorescence and floral meristems are all enlarged relative to wild type. The apical meristem can fasciate in the more severe mutant alleles, and this fasciation can occur prior to the transition to flowering. Flowers of clavata1 plants can have increased numbers of organs in all four whorls, and can also have additional whorls not present in wild-type flowers. Double mutant combinations of clavata1 with agamous, apetala2, apetala3 and pistillata indicate that CLAVATA1 controls the underlying floral meristem structure upon which these homeotic genes act. Double mutant combinations of clavata1 with apetala1 and leafy indicate CLAVATA1 plays a role in establishing and maintaining floral meristem identity, in addition to its role in controlling meristem size. In support of this, RNA expression patterns of AGAMOUS and APETALA1 are altered in clavata1 flowers.

Item Type:Article
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Meyerowitz, Elliot M.0000-0003-4798-5153
Additional Information:© 1993 The Company of Biologists Limited. Accepted 1 July 1993. We thank our colleagues Detlef Weigel, Tom Jack, Gary Drews, Joshua Levin, Leslie Sieburth, Caren Chang, Hajime Sakai, Robert Williams, Jose-Luis Riechmann and Susan Apostolaki for critical review of the manuscript. We also thank Martin Yanofsky for providing us with the AP1 probe prior to publication, and Pat Koen of the Electron Microscope Facility at Caltech for technical advice. This work was supported by United States National Science Foundation (NSF) grant number MCB-9204839 to E. M. M. S. E. C. was supported by an NSF Postdoctoral Fellowship in Plant Biology, and M. P. R. was a Howard Hughes Predoctoral Fellow.
Funding AgencyGrant Number
NSF Postdoctoral FellowshipUNSPECIFIED
Howard Hughes Medical Institute (HHMI)UNSPECIFIED
Subject Keywords:fasciation, flower, meristem, inflorescence, Arabidopsis, CLAVATA1
Issue or Number:2
Record Number:CaltechAUTHORS:20120223-141140046
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Official Citation:CLAVATA1, a regulator of meristem and flower development in Arabidopsis S.E. Clark, M.P. Running, E.M. Meyerowitz Development 1993 119: 397-418
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:29443
Deposited By: Tony Diaz
Deposited On:23 Feb 2012 23:21
Last Modified:03 Oct 2019 03:41

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