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Frontal Eye Field Neurons Assess Visual Stability Across Saccades

Crapse, Trinity B. and Sommer, Marc A. (2012) Frontal Eye Field Neurons Assess Visual Stability Across Saccades. Journal of Neuroscience, 32 (8). pp. 2835-2845. ISSN 0270-6474. PMCID PMC3566788. doi:10.1523/JNEUROSCI.1320-11.2012. https://resolver.caltech.edu/CaltechAUTHORS:20120327-073642211

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Abstract

The image on the retina may move because the eyes move, or because something in the visual scene moves. The brain is not fooled by this ambiguity. Even as we make saccades, we are able to detect whether visual objects remain stable or move. Here we test whether this ability to assess visual stability across saccades is present at the single-neuron level in the frontal eye field (FEF), an area that receives both visual input and information about imminent saccades. Our hypothesis was that neurons in the FEF report whether a visual stimulus remains stable or moves as a saccade is made. Monkeys made saccades in the presence of a visual stimulus outside of the receptive field. In some trials, the stimulus remained stable, but in other trials, it moved during the saccade. In every trial, the stimulus occupied the center of the receptive field after the saccade, thus evoking a reafferent visual response. We found that many FEF neurons signaled, in the strength and timing of their reafferent response, whether the stimulus had remained stable or moved. Reafferent responses were tuned for the amount of stimulus translation, and, in accordance with human psychophysics, tuning was better (more prevalent, stronger, and quicker) for stimuli that moved perpendicular, rather than parallel, to the saccade. Tuning was sometimes present as well for nonspatial transaccadic changes (in color, size, or both). Our results indicate that FEF neurons evaluate visual stability during saccades and may be general purpose detectors of transaccadic visual change.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1523/JNEUROSCI.1320-11.2012DOIArticle
http://www.ncbi.nlm.nih.gov/pmc/articles/pmc3566788/PubMed CentralArticle
Additional Information:© 2012 the authors. Received March 15, 2011; revised Nov. 23, 2011; accepted Dec. 20, 2011. Author contributions: T.B.C. and M.A.S. designed research; T.B.C. performed research; T.B.C. and M.A.S. analyzed data; T.B.C. and M.A.S. wrote the paper. The authors declare no competing financial interests. This work was supported by the NIH (Grant EY017592 to M.A.S.) and the University of Pittsburgh (Andrew Mellon Predoctoral Fellowship to T.B.C.).
Funders:
Funding AgencyGrant Number
NIHEY017592
University of PittsburghUNSPECIFIED
Issue or Number:8
PubMed Central ID:PMC3566788
DOI:10.1523/JNEUROSCI.1320-11.2012
Record Number:CaltechAUTHORS:20120327-073642211
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20120327-073642211
Official Citation: Trinity B. Crapse and Marc A. Sommer Frontal Eye Field Neurons Assess Visual Stability Across Saccades The Journal of Neuroscience, 22 February 2012, 32(8):2835-2845; doi:10.1523/JNEUROSCI.1320-11.2012
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:29852
Collection:CaltechAUTHORS
Deposited By: Ruth Sustaita
Deposited On:27 Mar 2012 14:53
Last Modified:09 Nov 2021 19:31

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