Khan, Sharaf Nawaz and Kim, Arim and Grubbs, Robert H. and Kwon, Yong-Uk (2012) Cross Metathesis Assisted Solid-Phase Synthesis of Glycopeptoids. Organic Letters, 14 (12). pp. 2952-2955. ISSN 1523-7060. doi:10.1021/ol300808c. https://resolver.caltech.edu/CaltechAUTHORS:20120710-131446965
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Abstract
A solid-phase synthesis of glycopeptoids was explored through olefin cross metathesis (CM). Peptoids and sugar derivatives with appropriate olefin moieties were coupled in the presence of an olefin metathesis catalyst to afford glycopeptoids in good yields. This systematic solid-phase CM study can provide facile access to the molecular sources of glycopeptidomimetics and postchemical modifications on various molecular scaffolds.
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| Additional Information: | © 2012 American Chemical Society. Received April 2, 2012. Publication Date (Web): June 7, 2012. This research was supported by the World Class University (WCU) program (R33-10169) and the Basic Science Research Program (2009-0068960) through the National Research Foundation of Korea funded by the Ministry of Education, Science and Technology. This work was also supported by the Ewha Global Top 5 Grant 2011 of Ewha Womans University. | |||||||||
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| Issue or Number: | 12 | |||||||||
| DOI: | 10.1021/ol300808c | |||||||||
| Record Number: | CaltechAUTHORS:20120710-131446965 | |||||||||
| Persistent URL: | https://resolver.caltech.edu/CaltechAUTHORS:20120710-131446965 | |||||||||
| Official Citation: | Cross Metathesis Assisted Solid-Phase Synthesis of Glycopeptoids Sharaf Nawaz Khan, Arim Kim, Robert H. Grubbs, and Yong-Uk Kwon Organic Letters201214 (12), 2952-2955 | |||||||||
| Usage Policy: | No commercial reproduction, distribution, display or performance rights in this work are provided. | |||||||||
| ID Code: | 32331 | |||||||||
| Collection: | CaltechAUTHORS | |||||||||
| Deposited By: | Tony Diaz | |||||||||
| Deposited On: | 12 Jul 2012 22:17 | |||||||||
| Last Modified: | 09 Nov 2021 21:26 |
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