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Polymer nanoparticle-based cancer therapeutics: from concept to clinic

Davis, M. E. (2010) Polymer nanoparticle-based cancer therapeutics: from concept to clinic. In: International Chemical Congress of Pacific Basin Societies (Pacifichem 2010), December 15-20, 2010, Honolulu, HI.

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Nanoparticle-based therapeutics contg. either small mol. anti-cancer agents (IT-101; entered Phase II) or siRNA (CALAA-01; in Phase I) are described. The key component in each nanoparticle is a cyclodextrin-contg. polymer that endows it with multifunctional behavior. Relationships between nanoparticle design and function in animal models are illustrated. Results from clin. trials are presented so show how nanoparticle-based therapeutics can provide interesting behavior in humans.

Item Type:Conference or Workshop Item (Paper)
Davis, M. E.0000-0001-8294-1477
Additional Information:© 2012 American Chemical Society.
Record Number:CaltechAUTHORS:20120815-152834973
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:33240
Deposited By: Tony Diaz
Deposited On:15 Aug 2012 23:04
Last Modified:09 Mar 2020 13:18

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