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Decision-Making in Individuals with Agenesis of the Corpus Callosum: Expectancy-Valence in the Iowa Gambling Task

Brown, Warren S. and Anderson, Luke B. and Symington, Melissa F. and Paul, Lynn K. (2012) Decision-Making in Individuals with Agenesis of the Corpus Callosum: Expectancy-Valence in the Iowa Gambling Task. Archives of Clinical Neuropsychology, 27 (5). pp. 532-544. ISSN 0887-6177. https://resolver.caltech.edu/CaltechAUTHORS:20120824-133825697

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Abstract

Individuals with agenesis of the corpus callosum (ACC) can have intelligence within the normal range, but nevertheless have deficiencies in decision-making and complex novel problem-solving. The specific nature of these problems is not yet clearly understood. The Iowa Gambling Task was used to test decision-making ability and problem-solving in 40 individuals with complete or partial ACC (full-scale intelligence quotient >80) and 26 control participants. The expectancy-valence (EV) model was applied to the trial-by-trial responses of each participant to elucidate differences in decision processes utilized by each group. The ACC group had a lower overall net gain and fewer advantageous choices than controls, but these differences were not statistically significant. Within the EV model, individuals with ACC exhibited significantly higher attention to losses, less consistency in their choice strategy, and greater frequency of switching between decks. They also showed a tendency to be more influenced by recent trials. This outcome is similar to that seen in individuals with Asperger's disorder. Taken together, these results suggest that individuals with ACC have difficulty in inferring game contingencies and forming a coherent selection strategy, implicating the corpus callosum in these decision processes.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1093/arclin/acs052DOIUNSPECIFIED
http://acn.oxfordjournals.org/content/27/5/532.shortPublisherUNSPECIFIED
ORCID:
AuthorORCID
Brown, Warren S.0000-0001-6142-5588
Paul, Lynn K.0000-0002-3128-8313
Additional Information:© 2012 The Author. Published by Oxford University Press. Accepted 16 May 2012. Advance Access publication on 21 June 2012. This work was supported in part by the Pfeiffer Family Foundation, Simons Foundation (SFARI-07-01 to R. Adolphs) and the National Alliance for Research on Schizophrenia and Depression (2009 Young Investigator Award to L.K.P.). Conflict of Interest: None declared. Parts of this paper are based on work done for the PhD dissertation of Melissa Symington (2003) and the MA thesis of Luke Anderson (2011) at the Fuller Graduate School of Psychology.
Funders:
Funding AgencyGrant Number
Pfeiffer Family FoundationUNSPECIFIED
Simons FoundationSFARI-07-01
National Alliance for Research on Schizophrenia and DepressionUNSPECIFIED
Subject Keywords:Executive function; Problem-solving; Strategy formation; Loss aversion
Issue or Number:5
Record Number:CaltechAUTHORS:20120824-133825697
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20120824-133825697
Official Citation: Warren S. Brown, Luke B. Anderson, Melissa F. Symington, and Lynn K. Paul Decision-Making in Individuals with Agenesis of the Corpus Callosum: Expectancy-Valence in the Iowa Gambling Task Arch Clin Neuropsychol (2012) 27(5): 532-544 first published online June 21, 2012 doi:10.1093/arclin/acs052
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:33520
Collection:CaltechAUTHORS
Deposited By: Ruth Sustaita
Deposited On:24 Aug 2012 21:23
Last Modified:03 Oct 2019 04:10

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