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Digital optical phase conjugation of fluorescence in turbid tissue

Vellekoop, Ivo M. and Cui, Meng and Yang, Changhuei (2012) Digital optical phase conjugation of fluorescence in turbid tissue. Applied Physics Letters, 101 (8). Art. No. 081108. ISSN 0003-6951. PMCID PMC3436909. doi:10.1063/1.4745775.

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We demonstrate a method for phase conjugating fluorescence. Our method, called reference free digital optical phase conjugation, can conjugate extremely weak, incoherent optical signals. It was used to phase conjugate fluorescent light originating from a bead covered with 0.5 mm of light-scattering tissue. The phase conjugated beam refocuses onto the bead and causes a local increase of over two orders of magnitude in the light intensity. Potential applications are in imaging, optical trapping, and targeted photochemical activation inside turbid tissue.

Item Type:Article
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URLURL TypeDescription DOIArticle CentralArticle
Yang, Changhuei0000-0001-8791-0354
Additional Information:© 2012 American Institute of Physics. Received 25 February 2012; accepted 30 July 2012; published online 22 August 2012. This work was funded by NIH under Grant No. 1DP2OD007307-01.
Funding AgencyGrant Number
Subject Keywords:biological tissues, biomedical optical imaging, fluorescence, light scattering, optical phase conjugation, photochemistry, radiation pressure, turbidity
Issue or Number:8
Classification Code:PACS: 87.63.L-; 42.65.Jx; 82.50.-m
PubMed Central ID:PMC3436909
Record Number:CaltechAUTHORS:20121005-104644595
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Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:34709
Deposited By: Tony Diaz
Deposited On:05 Oct 2012 20:16
Last Modified:09 Nov 2021 23:10

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