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Fighting cancer with nanoparticle medicines - The nanoscale matters

Davis, Mark E. (2012) Fighting cancer with nanoparticle medicines - The nanoscale matters. MRS Bulletin, 37 (9). pp. 828-835. ISSN 0883-7694. doi:10.1557/mrs.2012.202. https://resolver.caltech.edu/CaltechAUTHORS:20121018-110927602

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Abstract

Papyrus writings from 1600–1500 BC describe cancer and the attempts at treatment. Centuries later, cancer remains a devastating disease. Given the long history of difficulties in developing cancer therapies, why is there excitement about nanoparticle medicine (nanomedicines) for fighting cancer? This article describes the current understanding of why these engineered, nano-sized medicines, which are highly multifunctional chemical systems, have the potential to provide revolutionary ways to treat cancer. This point is illustrated by physical insights at the nanoscale that allow for the development of nanoparticles that can function in both animals and humans. The human data show how we have translated two independent nanoparticle cancer therapeutics from laboratory curiosities to experimental therapeutics in human clinical trials.


Item Type:Article
Related URLs:
URLURL TypeDescription
http://dx.doi.org/10.1557/mrs.2012.202 DOIUNSPECIFIED
http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=8691626PublisherUNSPECIFIED
ORCID:
AuthorORCID
Davis, Mark E.0000-0001-8294-1477
Additional Information:© 2012 Materials Research Society. Published online by Cambridge University Press: September 2012.
Subject Keywords:Nanoscale; biomedical; colloid
Issue or Number:9
DOI:10.1557/mrs.2012.202
Record Number:CaltechAUTHORS:20121018-110927602
Persistent URL:https://resolver.caltech.edu/CaltechAUTHORS:20121018-110927602
Usage Policy:No commercial reproduction, distribution, display or performance rights in this work are provided.
ID Code:34973
Collection:CaltechAUTHORS
Deposited By: Tony Diaz
Deposited On:18 Oct 2012 18:53
Last Modified:09 Nov 2021 23:11

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